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Search: WFRF:(Debette Stéphanie) > (2020-2023) > Twenty-seven-year t...

  • Wolters, Frank J (author)

Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/297497
  • https://gup.ub.gu.se/publication/297497URI
  • https://doi.org/10.1212/WNL.0000000000010022DOI

Supplementary language notes

  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • To determine changes in the incidence of dementia between 1988 and 2015.This analysis was performed in aggregated data from individuals >65 years of age in 7 population-based cohort studies in the United States and Europe from the Alzheimer Cohort Consortium. First, we calculated age- and sex-specific incidence rates for all-cause dementia, and then defined nonoverlapping 5-year epochs within each study to determine trends in incidence. Estimates of change per 10-year interval were pooled and results are presented combined and stratified by sex.Of 49,202 individuals, 4,253 (8.6%) developed dementia. The incidence rate of dementia increased with age, similarly for women and men, ranging from about 4 per 1,000 person-years in individuals aged 65-69 years to 65 per 1,000 person-years for those aged 85-89 years. The incidence rate of dementia declined by 13% per calendar decade (95% confidence interval [CI], 7%-19%), consistently across studies, and somewhat more pronouncedly in men than in women (24% [95% CI 14%-32%] vs 8% [0%-15%]).The incidence rate of dementia in Europe and North America has declined by 13% per decade over the past 25 years, consistently across studies. Incidence is similar for men and women, although declines were somewhat more profound in men. These observations call for sustained efforts to finding the causes for this decline, as well as determining their validity in geographically and ethnically diverse populations.

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  • Chibnik, Lori B (author)
  • Waziry, Reem (author)
  • Anderson, Roy (author)
  • Berr, Claudine (author)
  • Beiser, Alexa (author)
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  • Bos, Daniel (author)
  • Brayne, Carol (author)
  • Dartigues, Jean-François (author)
  • Darweesh, Sirwan K L (author)
  • Davis-Plourde, Kendra L (author)
  • de Wolf, Frank (author)
  • Debette, Stephanie (author)
  • Dufouil, Carole (author)
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  • Helmer, Catherine (author)
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  • Ikram, M Kamran (author)
  • Joas, Erik,1983Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centrum för åldrande och hälsa (AgeCap),Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Centre for Ageing and Health (Agecap)(Swepub:gu)xjoaer (author)
  • Kern, SilkeGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centrum för åldrande och hälsa (AgeCap),Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Centre for Ageing and Health (Agecap)(Swepub:gu)xkersi (author)
  • Kuller, Lewis H (author)
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  • Lopez, Oscar L (author)
  • Matthews, Fiona E (author)
  • McRae-McKee, Kevin (author)
  • Meirelles, Osorio (author)
  • Mosley, Thomas H (author)
  • Pase, Matthew P (author)
  • Psaty, Bruce M (author)
  • Satizabal, Claudia L (author)
  • Seshadri, Sudha (author)
  • Skoog, Ingmar,1954Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xskooi (author)
  • Stephan, Blossom C M (author)
  • Wetterberg, HannaGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centrum för åldrande och hälsa (AgeCap),Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Centre for Ageing and Health (Agecap)(Swepub:gu)xohann (author)
  • Wong, Mei Mei (author)
  • Zettergren, Anna,1978Gothenburg University,Göteborgs universitet,Centrum för åldrande och hälsa (AgeCap),Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centre for Ageing and Health (Agecap),Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xhakan (author)
  • Hofman, Albert (author)
  • Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi (creator_code:org_t)

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