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  • Almqvist, LinnéaUmeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden (författare)

Remission of adult-onset asthma is rare: a 15-year follow-up study

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • 2020-09-24
  • European Respiratory Society (ERS),2020

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/301302
  • https://gup.ub.gu.se/publication/301302URI
  • https://doi.org/10.1183/23120541.00620-2020DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-179059URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-81884URI

Kompletterande språkuppgifter

  • Språk:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Validerad;2020;Nivå 2;2020-12-07 (alebob)
  • Background: There are few long-term clinical follow-up studies of adult-onset asthma. The aim of this article was to study clinical characteristics of adult-onset asthma in relation to remission and persistence of the disease in a 15-year follow-up. Methods: A cohort of 309 adults aged 20-60 years with asthma onset during the last 12 months verified by bronchial variability, was recruited between 1995 and 1999 from the general population in northern Sweden. The cohort was followed-up in 2003 (n=250) and between 2012 and 2014 (n=205). Structured interviews and spirometry were performed at recruitment and the follow-ups. Bronchial hyperreactivity (BHR) and skin-prick tests were performed at recruitment and blood samples were collected at the last follow-up. Remission of asthma was defined as no asthma symptoms and no use of asthma medication during the last 12 months. Results: Of eight individuals in remission in 2003, five had relapsed between 2012 and 2014 and in total, 23 (11%) were in remission, while 182 had persistent asthma. Those in remission had higher mean forced expiratory volume in 1 s % predicted at recruitment than those with persistent asthma (94.6 versus 88.3, p=0.034), fewer had severe BHR (27.3% versus 50.9%, p=0.037) and they had less body mass index increase (+1.6 versus +3.0, p=0.054). Of those with persistent asthma, 13% had uncontrolled asthma and they had higher levels of blood neutrophils than those with partly controlled or controlled asthma. Conclusion: Higher forced expiratory volume in 1 s % predicted and less-severe BHR was associated with remission of adult-onset asthma, but still, the proportion in remission in this 15-year follow-up was low.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Rönmark, EvaUmeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden(Swepub:umu)evra0004 (författare)
  • Stridsman, CarolineUmeå universitet,Avdelningen för medicin,Dept of Public Health and Clinical Medicine, Division of Medicine, The OLIN Unit, Umeå University, Umeå, Sweden(Swepub:umu)cast0052 (författare)
  • Backman, HelenaLuleå tekniska universitet,Umeå universitet,Avdelningen för hållbar hälsa,Department of Health Sciences, Luleå University of Technology, Luleå, Sweden,Omvårdnad och medicinsk teknik,Dept of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden(Swepub:ltu)helbac (författare)
  • Lindberg, AnneUmeå universitet,Avdelningen för medicin,Dept of Public Health and Clinical Medicine, Division of Medicine, The OLIN Unit, Umeå University, Umeå, Sweden(Swepub:umu)anelig02 (författare)
  • Lundbäck, Bo,1948Gothenburg University,Göteborgs universitet,Krefting Research Centre,Institutionen för medicin,Institute of Medicine,Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenborg, Sweden(Swepub:gu)xlunbo (författare)
  • Hedman, Linnéa,1979-Luleå tekniska universitet,Umeå universitet,Avdelningen för hållbar hälsa,Department of Health Sciences, Luleå University of Technology, Luleå, Sweden,Omvårdnad och medicinsk teknik,Dept of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden(Swepub:ltu)linhed (författare)
  • Umeå universitetAvdelningen för hållbar hälsa (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Erj Open Research: European Respiratory Society (ERS)6:42312-0541

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