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Sökning: WFRF:(Kuja Halkola Ralf) > (2021) > Internalizing and n...

Internalizing and neurodevelopmental problems in young people: Educational outcomes in a large population-based cohort of twins

Doering, Sabrina (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Centrum för etik, juridik och mental hälsa,Institute of Neuroscience and Physiology,Centre for Ethics, Law, and Mental Health
Lichtenstein, Paul (författare)
Karolinska Institutet
Gillberg, Christopher, 1950 (författare)
Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre
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Kuja-Halkola, Ralf (författare)
Karolinska Institutet
Lundström, Sebastian (författare)
Gothenburg University,Göteborgs universitet,Gillbergcentrum,Centrum för etik, juridik och mental hälsa,Gillberg Neuropsychiatry Centre,Centre for Ethics, Law, and Mental Health
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 (creator_code:org_t)
Elsevier BV, 2021
2021
Engelska.
Ingår i: Psychiatry Research. - : Elsevier BV. - 0165-1781 .- 1872-7123. ; 298
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • © 2021 The Authors Adolescent internalizing problems such as anxiety and depression have been associated with subsequent educational underachievement. However, it has not been investigated if the association is accounted for by neurodevelopmental disorders (NDDs, i.e., attention-deficit/hyperactivity disorder, autism spectrum disorder, developmental coordination disorder, tic disorder, learning disorder). This study is the first to describe the relationship between internalizing problems at age 15 and educational outcomes in later adolescence while controlling for a wide range of NDDs in childhood, and applying a genetically sensitive design. We used the nation-wide population-based Child and Adolescent Twin Study in Sweden, comprising 4997 fifteen-year-old Swedish twins born between 1994 and 1998. Internalizing problems and NDDs were measured with parental report. Educational outcomes were merit rating and upper secondary education eligibility, retrieved from the National School Register. Internalizing problems at age 15 were found to be negatively associated with educational outcomes in later adolescence. Additive genetics accounted for 89% of the covariation between internalizing problems and merit rating, out of which roughly half were unique genetic effects of internalizing problems and the remaining half due to NDDs. In conclusion, internalizing problems form an important risk factor for subsequent educational underachievement, going beyond the risk conferred by childhood NDDs.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Anxiety
depression
Education
Genetics
Internalizing disorders
Neurodevelopmental disorders

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