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Cumulative Occupati...
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Lytras, T.Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.
(författare)
Cumulative Occupational Exposures and Lung-Function Decline in Two Large General-Population Cohorts
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
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New York :American Thorax Society,2021
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/302563
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https://gup.ub.gu.se/publication/302563URI
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https://doi.org/10.1513/AnnalsATS.202002-113OCDOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177391URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-437084URI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Rationale: Few longitudinal studies have assessed the relationship between occupational exposures and lung-function decline in the general population with a sufficiently long follow-up. Objectives: To examine the potential association in two large cohorts: the ECRHS (European Community Respiratory Health Survey) and the SAPALDIA (Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults). Methods: General-population samples of individuals aged 18 to 62 were randomly selected in 1991-1993 and followed up approximately 10 and 20 years later. Spirometry (without bronchodilation) was performed at each visit. Coded complete job histories during follow-up visits were linked to a job-exposure matrix, generating cumulative exposure estimates for 12 occupational exposures. Forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were jointly modeled in linear mixed-effects models, fitted in a Bayesian framework, taking into account age and smoking. Results: A total of 40,024 lung-function measurements from 17,833 study participants were analyzed. We found accelerated declines in FEV1 and the FEV1/FVC ratio for exposure to biological dust, mineral dust, and metals (FEV1 = -15.1 ml, -14.4 ml, and -18.7 ml, respectively; and FEV1/FVC ratio = -0.52%, -0.43%, and -0.36%, respectively; per 25 intensity-years of exposure). These declines were comparable in magnitude with those associated with long-term smoking. No effect modification by sex or smoking status was identified. Findings were similar between the ECRHS and the SAPALDIA cohorts. Conclusions: Our results greatly strengthen the evidence base implicating occupation, independent of smoking, as a risk factor for lung-function decline. This highlights the need to prevent or control these exposures in the workplace.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Beckmeyer-Borowko, A.Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Basel, Switzerland.
(författare)
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Kogevinas, M.Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol & Salud Publ, Madrid, Spain.;Hosp del Mar Med Res Inst, Barcelona, Spain.
(författare)
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Kromhout, H.Univ Utrecht, IRAS, Utrecht, Netherlands.
(författare)
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Carsin, A. E.Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol & Salud Publ, Madrid, Spain.
(författare)
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Anto, J. M.Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol & Salud Publ, Madrid, Spain.;Hosp del Mar Med Res Inst, Barcelona, Spain.
(författare)
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Bentouhami, H.Univ Antwerp, Fac Med & Hlth Sci, Dept Epidemiol & Social Med, Social Epidemiol & Hlth Policy, Antwerp, Belgium.
(författare)
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Weyler, J.Univ Antwerp, Fac Med & Hlth Sci, Dept Epidemiol & Social Med, Social Epidemiol & Hlth Policy, Antwerp, Belgium.
(författare)
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Heinrich, J.Ludwig Maximilians Univ Munchen, Inst & Outpatient Clin Occupat Social & Environm, Univ Hosp, Munich, Germany.;German Ctr Lung Res, Comprehens Pneumol Ctr Munich, Munich, Germany.
(författare)
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Nowak, D.Ludwig Maximilians Univ Munchen, Inst & Outpatient Clin Occupat Social & Environm, Univ Hosp, Munich, Germany.;German Ctr Lung Res, Comprehens Pneumol Ctr Munich, Munich, Germany.
(författare)
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Urrutia, I.Galdakao Hosp, Pulmonol Dept, Galdakao, Spain.
(författare)
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Martinez-Moratalla, J.Complejo Hosp Univ, Serv Neumol, Albacete, Spain.;Univ Castilla La Mancha, Albacete Fac Med, Ciudad Real, Spain.
(författare)
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Gullon, J. A.San Agustin Univ Hosp, Resp Dept, Aviles, Asturias, Spain.
(författare)
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Vega, A. P.Juan Ramon Jimenez Univ Hosp, Pulmonol & Allergy Clin Unit, Huelva, Spain.
(författare)
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Semjen, C. R.Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, Team EPICENE, INSERM,UMR 1219, Bordeaux, France.
(författare)
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Pin, I.CHU Grenoble Alpes, Dept Pediat, Grenoble, France.;INSERM, U1209, IAB, Team Environm Epidemiol Appl Reprod & Resp Hlth, Grenoble, France.;Univ Grenoble Alpes, Grenoble, France.
(författare)
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Demoly, P.Univ Hosp Montpellier, Montpellier, France.;Sorbonne Univ, INSERM UMR S 1136, Paris, France.,Univ Calif San Francisco, San Francisco, CA 94143 USA.;San Francisco Vet Affairs Hlth Care Syst, San Francisco, CA USA.
(författare)
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Leynaert, B.Univ Paris Diderot, Inserm UMR 1152, Equipe Epidemiol, Paris, France.
(författare)
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Villani, S.Univ Pavia, Dept Publ Hlth Expt & Forens Med, Unit Biostat & Clin Epidemiol, Pavia, Italy.
(författare)
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Gislason, T.Landspitali Univ Hosp, Dept Resp Med & Sleep, IS-108 Reykjavik, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.
(författare)
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Svanes, O.Univ Bergen, Dept Clin Sci, Bergen, Norway.
(författare)
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Holm, M.Sahlgrens Univ Hosp, Dept Occupat & Environm Med, Gothenburg, Sweden.
(författare)
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Forsberg, BertilUmeå universitet,Avdelningen för hållbar hälsa,Umeå Univ, Dept Publ Hlth & Clin Med, Sect Sustainable Hlth, Umeå, Sweden.(Swepub:umu)befo0001
(författare)
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Norbäck, DanUppsala universitet,Arbets- och miljömedicin(Swepub:uu)dagnorba
(författare)
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Mehta, A. J.Univ Copenhagen, Dept Publ Hlth, Sect Epidemiol, Copenhagen, Denmark.
(författare)
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Keidel, D.Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Basel, Switzerland.
(författare)
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Vernez, D.Univ Lausanne, Ctr Primary Care & Publ Hlth, Lausanne, Switzerland.
(författare)
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Benke, G.Monash Univ, Monash Ctr Occupat & Environm Hlth, Sch Publ Hlth & Prevent Med, Victoria, Australia.
(författare)
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Jogi, R.Tartu Univ Hosp, Lung Clin, Tartu, Estonia.
(författare)
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Torén, Kjell,1952Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sahlgrenska Acad, Sch Publ Hlth & Community Med, Occupat & Environm Med, Gothenburg, Sweden.(Swepub:gu)xtorkj
(författare)
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Sigsgaard, T.Aarhus Univ, Danish Ramazzini Ctr, Dept Publ Hlth, Sect Environm Occupat & Hlth, Aarhus, Denmark.
(författare)
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Schlunssen, V.Aarhus Univ, Danish Ramazzini Ctr, Dept Publ Hlth, Sect Environm Occupat & Hlth, Aarhus, Denmark.;Natl Res Ctr Working Environm, Copenhagen, Denmark.
(författare)
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Olivieri, M.Univ Verona, Dept Diagnost & Publ Hlth, Unit Occupat Med, Verona, Italy.
(författare)
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Blanc, P. D.
(författare)
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Watkins, J.Cardiff Univ, Sch Med, Publ Hlth Wales, Cardiff, Wales.
(författare)
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Bono, R.Univ Turin, Dept Publ Hlth & Pediat, Turin, Italy.
(författare)
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Squillacioti, G.Univ Turin, Dept Publ Hlth & Pediat, Turin, Italy.
(författare)
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Buist, A. S.Oregon Hlth & Sci Univ, Pulm & Crit Care Med, Portland, OR 97201 USA.
(författare)
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Vermeulen, R.Univ Utrecht, IRAS, Utrecht, Netherlands.
(författare)
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Jarvis, D.Imperial Coll London, Populat Hlth & Occupat Dis, Natl Heart & Lung Inst, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.
(författare)
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Probst-Hensch, N.Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Basel, Switzerland.
(författare)
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Zock, J. P.Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol & Salud Publ, Madrid, Spain.
(författare)
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Svanes, Øistein
(författare)
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Barcelona Inst Global Hlth, Barcelona Biomed Res Pk PRBB,Doctor Aiguader 88, Barcelona 08003, Spain.;Univ Pompeu Fabra, Barcelona, Spain.Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Basel, Switzerland.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Annals of the American Thoracic SocietyNew York : American Thorax Society18:2, s. 238-2461546-32222329-69332325-66211943-5665
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Till lärosätets databas
- Av författaren/redakt...
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Lytras, T.
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Beckmeyer-Borowk ...
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Kogevinas, M.
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Kromhout, H.
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Carsin, A. E.
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Anto, J. M.
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visa fler...
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Bentouhami, H.
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Weyler, J.
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Heinrich, J.
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Nowak, D.
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Urrutia, I.
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Martinez-Moratal ...
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Gullon, J. A.
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Vega, A. P.
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Semjen, C. R.
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Pin, I.
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Demoly, P.
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Leynaert, B.
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Villani, S.
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Gislason, T.
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Svanes, O.
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Holm, M.
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Forsberg, Bertil
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Norbäck, Dan
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Mehta, A. J.
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Keidel, D.
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Vernez, D.
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Benke, G.
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Jogi, R.
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Torén, Kjell, 19 ...
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Sigsgaard, T.
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Schlunssen, V.
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Olivieri, M.
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Blanc, P. D.
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Watkins, J.
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Bono, R.
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Squillacioti, G.
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Buist, A. S.
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Vermeulen, R.
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Jarvis, D.
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Probst-Hensch, N ...
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Zock, J. P.
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Svanes, Øistein
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visa färre...
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