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Urinary continence ...
Urinary continence recovery and oncological outcomes after surgery for prostate cancer analysed by risk category: results from the LAParoscopic prostatectomy robot and open trial
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- Hagman, A. (författare)
- Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Eugeniavagen 3, S-17176 Solna, Sweden.
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- Lantz, A. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.
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- Carlsson, S. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.
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- Höijer, Jonas (författare)
- Uppsala universitet,Uppsala University,Ortopedi
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- Stranne, Johan, 1970 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Sahlgrenska University Hospital,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Urol, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Urol, Gothenburg, Region Vastra G, Sweden.
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- Tyritzis, S. I. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.
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- Haglind, Eva, 1947 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Sahlgrenska University Hospital,Univ Gothenburg, Scandinavian Surg Outcomes Res Grp, Sahlgrenska Acad, Dept Surg,Inst Clin Sci, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Surg, Gothenburg, Region Vastra G, Sweden.
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- Bjartell, Anders (författare)
- Lund University,Lunds universitet,Urologisk cancerforskning, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urological cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Urol, Lund, Sweden.
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- Hugosson, Jonas, 1955 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Urol, Gothenburg, Sweden.
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- Akre, O. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.
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- Steineck, Gunnar, 1952 (författare)
- Karolinska Institute,University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology,Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Div Clin Canc Epidemiol,Dept Oncol, Gothenburg, Sweden.;Karolinska Inst, Div Clin Canc Epidemiol, Dept Pathol & Oncol, Stockholm, Sweden.
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- Wiklund, P. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Icahn School of Medicine at Mount Sinai,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med Surg & Pelv Canc, S-17176 Stockholm, Sweden.;Icahn Sch Med, Mt Sinai Hlth Syst, New York, NY USA.
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(creator_code:org_t)
- 2021-03-20
- 2021
- Engelska.
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Ingår i: World Journal of Urology. - : Springer Science and Business Media LLC. - 0724-4983 .- 1433-8726. ; 39:9, s. 3239-3249
- Relaterad länk:
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http://dx.doi.org/10...
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Purpose To evaluate urinary continence (UC) recovery and oncological outcomes in different risk-groups after robot-assisted radical prostatectomy (RALP) and open retropubic radical prostatectomy (RRP). Patients and methods We analysed 2650 men with prostate cancer from seven open (n = 805) and seven robotic (n = 1845) Swedish centres between 2008 and 2011 in a prospective non-randomised trial, LAPPRO. UC recovery was defined as change of pads less than once in 24 h. Information was collected through validated questionnaires. Rate of positive surgical margins (PSM) and biochemical recurrence (BCR), defined as prostate-specific antigen (PSA) > 0.25 mg/ml, were recorded. We stratified patients into two risk groups (low-intermediate and high risk) based on the D'Amico risk classification system. Result Among men with high-risk prostate cancer, we found significantly higher rates of UC recovery up to 24 months after RRP compared to RALP (66.1% vs 60.5%) RR 0.85 (CI 95% 0.73-0.99) while PSM was more frequent after RRP compared to RALP (46.8% vs 23.5%) RR 1.56 (CI 95% 1.10-2.21). In the same group no significant difference was seen in BCR. Overall, however, BCR was significantly more common after RRP compared to RALP at 24 months (9.8% vs 6.6%) RR 1.43 (Cl 95% 1.08-1.89). The limitations of this study are its non-randomized design and the relatively short time of follow-up. Conclusions Our study indicates that men with high-risk tumour operated with open surgery had better urinary continence recovery but with a higher risk of PSM than after robotic-assisted laparoscopic surgery. No significant difference was seen in biochemical recurrence.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Prostate cancer
- Robot-assisted surgery
- Prostatectomy
- Recurrence
- Urinary incontinence
- Urology & Nephrology
- Prostate cancer
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Hagman, A.
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Lantz, A.
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Carlsson, S.
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Höijer, Jonas
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Stranne, Johan, ...
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Tyritzis, S. I.
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visa fler...
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Haglind, Eva, 19 ...
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Bjartell, Anders
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Hugosson, Jonas, ...
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Akre, O.
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Steineck, Gunnar ...
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Wiklund, P.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
- Artiklar i publikationen
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World Journal of ...
- Av lärosätet
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Göteborgs universitet
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Lunds universitet
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Uppsala universitet
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Karolinska Institutet