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  • Pallon, JonLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Region Kronoberg,Lund Univ, Sweden; Dept Res & Dev, Sweden; Inst Kansliet Klin Vetenskaper, Sweden (author)

Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-03-08
  • Springer Science and Business Media LLC,2021

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/304171
  • https://gup.ub.gu.se/publication/304171URI
  • https://doi.org/10.1007/s15010-021-01595-9DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-90334URI
  • https://lup.lub.lu.se/record/b88abf7a-4f4f-406b-bfb5-7d06c9f2ea3fURI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-174894URI

Supplementary language notes

  • Language:English

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Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies:Lund University UK Research & Innovation (UKRI)Medical Research Council UK (MRC) Region Kronoberg, Sweden 
  • Funding Agencies|Lund University; Swedish Public Health Agency; Medical Research Council of Southeast SwedenUK Research & Innovation (UKRI)Medical Research Council UK (MRC); Region Kronoberg, Sweden
  • Purpose Most studies on paediatric pharyngotonsillitis focus on group A streptococci. This study, however, analyses a broad spectrum of bacteria and viruses related to paediatric pharyngotonsillitis and evaluates their associated clinical symptoms and courses. Methods This observational prospective study in primary healthcare includes 77 children aged < 15 with a sore throat and 34 asymptomatic children, all of whom were sampled from the tonsils with an E-swab(R) for analysis with culture and PCR for 14 bacteria and 15 viruses. Patients were evaluated clinically, and their symptoms recorded in diaries for 10 days. Participants were followed up for 3 months by reviewing medical records. Results A pathogen was detected in 86% of patients and in 71% of controls (P = 0.06). Bacteria were found in 69% of patients and 59% of controls (P = 0.3), and viruses in 36% and 26%, respectively (P = 0.3). Group A streptococci was the most common finding, with a prevalence of 49% and 32%, respectively (P = 0.1). Clinical signs were not useful for distinguishing pathogens. None of the controls and 16% of the patients reconsulted for a sore throat within 3 months. Conclusion Bacteria were more common than viruses in both study groups. The high rate of pathogens in asymptomatic children interferes with diagnoses based on aetiology.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Sundqvist, Martin,1974-Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Laboratory Medicin,Orebro Univ, Sweden(Swepub:oru)mist (author)
  • Rööst, MattiasLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Region Kronoberg,Lund Univ, Sweden; Dept Res & Dev, Sweden(Swepub:lu)med-mar (author)
  • Danielsson, P.Cityläkarna Primary Healthcare Centre, Region Kalmar County, Kalmar, Sweden,Kalmar County Hospital,Citylakarna Primary Healthcare Ctr, Sweden (author)
  • Neumark, T.Region Kalmar County, Kalmar, Sweden,Kalmar County Hospital (author)
  • Skovbjerg, Susann,1973University of Gothenburg,Gothenburg University,Göteborgs universitet,CARe - Centrum för antibiotikaresistensforskning,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Centre for antibiotic resistance research, CARe,Institute of Biomedicine, Department of Infectious Medicine,Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Microbiology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; Centre for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sweden; Sahlgrens Univ Hosp, Sweden(Swepub:gu)xjsusm (author)
  • Svedin, J.Anderslöv Primary Healthcare Centre, Region Skåne, Anderslöv, Sweden,Anderslov Primary Healthcare Ctr, Sweden (author)
  • Hedin, KatarinaLinköpings universitet,Linköping University,Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Lund Univ, Sweden(Swepub:liu)kathe53 (author)
  • Allmänmedicin och samhällsmedicinForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Infection: Springer Science and Business Media LLC49:4, s. 715-7240300-81261439-0973

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