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Quality of life in ...
Quality of life in pediatric patients with obsessive-compulsive disorder during and 3 years after stepped-care treatment
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Jensen, S. (författare)
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Hybel, K. A. (författare)
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Hojgaard, Drma (författare)
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Nissen, J. B. (författare)
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Weidle, B. (författare)
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- Ivarsson, Tord, 1946 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences
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Skarphedinsson, G. (författare)
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- Melin, Karin, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences
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Torp, N. C. (författare)
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Carlsen, A. H. (författare)
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Mortensen, E. L. (författare)
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- Lenhard, F. (författare)
- Karolinska Institutet
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Compton, S. (författare)
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Thomsen, P. H. (författare)
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(creator_code:org_t)
- 2021-04-21
- 2022
- Engelska.
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Ingår i: European Child & Adolescent Psychiatry. - : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 31:9, s. 1377-1389
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
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- The present study aimed to investigate the long-term quality of life (QoL) in a large sample of pediatric obsessive-compulsive disorder (OCD) patients. The study included 220 pediatric OCD patients from the Nordic Long-term OCD Treatment Study (NordLOTS) who were evaluated at seven time points before, during, and after stepped-care treatment over a 3-year follow-up period. Data from three symptom severity trajectory classes formed the basis of the QoL evaluation: acute (n = 127, N = 147), slow (n = 46, N = 63), and limited responders (n = 47, N = 59). Patients' QoL was assessed using parent and child ratings of the revised Questionnaire for Measuring Health-related Quality of Life in Children and Adolescents (KINDL-R). QoL was analyzed by trajectory class using a random mixed effects model. The association between pre-treatment factors and long-term QoL was investigated across classes in a multivariate model. Three years after treatment, the acute responder class had reached QoL levels from a general population, whereas the limited responder class had not. The slow responder class reached norm levels for the child-rated QoL only. Higher levels of co-occurring externalizing symptoms before treatment were associated with lower parent-rated QoL during follow-up, while adolescence and higher levels of co-occurring internalizing symptoms were associated with lower child-rated QoL during follow-up. For some patients, residual OCD symptoms in the years after treatment, even at levels below assumed clinical significance, are associated with compromised QoL. Co-occurring symptoms could be part of the explanation. Assessing QoL after OCD treatment, beyond the clinician-rated symptom severity, could detect patients in need of further treatment and/or assessment. Trial registry: Nordic Long-term Obsessive-Compulsive Disorder (OCD) Treatment Study; ; ISRCTN66385119.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- Quality of life
- Obsessive-compulsive disorder
- Children and
- adolescents
- Long-term
- Treatment outcome
- Stepped-care treatment
- Psychology
- Pediatrics
- Psychiatry
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Jensen, S.
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Hybel, K. A.
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Hojgaard, Drma
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Nissen, J. B.
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Weidle, B.
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Ivarsson, Tord, ...
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visa fler...
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Skarphedinsson, ...
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Melin, Karin, 19 ...
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Torp, N. C.
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Carlsen, A. H.
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Mortensen, E. L.
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Lenhard, F.
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Compton, S.
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Thomsen, P. H.
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visa färre...
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European Child & ...
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Göteborgs universitet
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Karolinska Institutet