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Migraine: disease c...
Migraine: disease characterisation, biomarkers, and precision medicine
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Ashina, M. (author)
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Terwindt, G. M. (author)
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Al-Karagholi, M. A. M. (author)
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de Boer, I. (author)
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Lee, M. J. (author)
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Hay, D. L. (author)
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Schulte, L. H. (author)
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- Hadjikhani, Nouchine, 1966 (author)
- Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre
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Sinclair, A. J. (author)
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Ashina, H. (author)
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Schwedt, T. J. (author)
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Goadsby, P. J. (author)
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(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- English.
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In: The Lancet. - : Elsevier BV. - 0140-6736. ; 397:10283, s. 1496-1504
- Related links:
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http://pure-oai.bham...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria. A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine, including the underlying genetic and neurobiological factors. This complexity has generated momentum for biomarker research to improve disease characterisation and identify novel drug targets. In this Series paper, we present the progress that has been made in the search for biomarkers of migraine within genetics, provocation modelling, biochemistry, and neuroimaging research. Additionally, we outline challenges and future directions for each biomarker modality. We also discuss the advances made in combining and integrating data from multiple biomarker modalities. These efforts contribute to developing precision medicine that can be applied to future patients with migraine.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- gene-related peptide
- onabotulinumtoxin type-a
- brain-stem activation
- network connectivity
- peripheral-blood
- functional mri
- attacks
- aura
- pain
- headache
- General & Internal Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
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The Lancet
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- By the author/editor
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Ashina, M.
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Terwindt, G. M.
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Al-Karagholi, M. ...
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de Boer, I.
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Lee, M. J.
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Hay, D. L.
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show more...
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Schulte, L. H.
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Hadjikhani, Nouc ...
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Sinclair, A. J.
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Ashina, H.
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Schwedt, T. J.
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Goadsby, P. J.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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The Lancet
- By the university
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University of Gothenburg