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Sökning: id:"swepub:oai:gup.ub.gu.se/306609" > Artificial intellig...

  • Borrelli, P.Sahlgrenska universitetssjukhuset,Sahlgrenska University Hospital (författare)

Artificial intelligence-aided CT segmentation for body composition analysis: a validation study

  • Artikel/kapitelEngelska2021

Förlag, utgivningsår, omfång ...

  • 2021-03-11
  • Springer Science and Business Media LLC,2021

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/306609
  • https://gup.ub.gu.se/publication/306609URI
  • https://doi.org/10.1186/s41747-021-00210-8DOI
  • https://research.chalmers.se/publication/522880URI
  • https://lup.lub.lu.se/record/d92f3b81-03cc-40a7-9f32-872248f3d924URI

Kompletterande språkuppgifter

  • Språk:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • BackgroundBody composition is associated with survival outcome in oncological patients, but it is not routinely calculated. Manual segmentation of subcutaneous adipose tissue (SAT) and muscle is time-consuming and therefore limited to a single CT slice. Our goal was to develop an artificial-intelligence (AI)-based method for automated quantification of three-dimensional SAT and muscle volumes from CT images.MethodsEthical approvals from Gothenburg and Lund Universities were obtained. Convolutional neural networks were trained to segment SAT and muscle using manual segmentations on CT images from a training group of 50 patients. The method was applied to a separate test group of 74 cancer patients, who had two CT studies each with a median interval between the studies of 3days. Manual segmentations in a single CT slice were used for comparison. The accuracy was measured as overlap between the automated and manual segmentations.ResultsThe accuracy of the AI method was 0.96 for SAT and 0.94 for muscle. The average differences in volumes were significantly lower than the corresponding differences in areas in a single CT slice: 1.8% versus 5.0% (p <0.001) for SAT and 1.9% versus 3.9% (p < 0.001) for muscle. The 95% confidence intervals for predicted volumes in an individual subject from the corresponding single CT slice areas were in the order of 20%.Conclusions The AI-based tool for quantification of SAT and muscle volumes showed high accuracy and reproducibility and provided a body composition analysis that is more relevant than manual analysis of a single CT slice.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Kaboteh, R.Sahlgrenska universitetssjukhuset,Sahlgrenska University Hospital (författare)
  • Enqvist, Olof,1981Chalmers University of Technology,Eigenvision AB(Swepub:cth)enolof (författare)
  • Ulén, JohannesChalmers University of Technology(Swepub:lu)math-jsu (författare)
  • Trägårdh, ElinLund University,Lunds universitet,Nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Nuclear medicine, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital(Swepub:lu)klin-etr (författare)
  • Kjölhede, Henrik,1981Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,University of Gothenburg,Sahlgrenska universitetssjukhuset,Sahlgrenska University Hospital(Swepub:lu)med-hrk (författare)
  • Edenbrandt, Lars,1957Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska universitetssjukhuset,Sahlgrenska University Hospital,University of Gothenburg(Swepub:lu)klfy-led (författare)
  • Sahlgrenska universitetssjukhusetSahlgrenska University Hospital (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:European Radiology Experimental: Springer Science and Business Media LLC5:12509-9280

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