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A decade of improve...
A decade of improved glycemic control in young children with type 1 diabetes: A population-based cohort study
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- Sundberg, Frida (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden; Sahlgrenska Academy, Institute of Clinical Sciences, University of Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden
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- Nåtman, J. (author)
- Center of Registers Västra Götaland, Gothenburg, Sweden,Ctr Registers Vastra Gotaland, Sweden
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- Franzén, Stefan, 1967 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Center of Registers Västra Götaland, Gothenburg, Sweden; Health Metrics Unit, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Ctr Registers Vastra Gotaland, Sweden; Univ Gothenburg, Sweden
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- Åkesson, Karin (author)
- Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Ryhov Cty Hosp, Sweden
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- Särnblad, Stefan, 1963- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Pediatrics, University Hospital Örebro, Örebro, Sweden,Univ Hosp Orebro, Sweden; Orebro Univ, Sweden
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(creator_code:org_t)
- 2021-05-06
- 2021
- English.
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In: Pediatric Diabetes. - : Hindawi Limited. - 1399-543X .- 1399-5448. ; 22:5, s. 742-748
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Abstract
Subject headings
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- Background: Early-onset type 1 diabetes (T1D) is associated with high risk of early cardiovascular complications and premature death. The strongest modifiable risk factor is HbA1c. Other modifiable factors, such as overweight, also increase the risk of complications. During the last decade, the introduction of continuous glucose monitoring (CGM) has offered new options in the treatment of T1D. Objective: To compare treatment outcomes in children younger than 7 years with T1D in Sweden in two separate cohorts: one in 2008 and one in 2018. Methods: All children in the national pediatric diabetes registry (SWEDIABKIDS) younger than 7 years with T1D were included. Data from 2008 and 2018 were analyzed. Results: Data were available on 666 children (45% girls) in 2008 and 779 children (45% girls) in 2018. Mean age was 5.6 (1.4) versus 5.5 (1.4) years and mean diabetes duration 2.3 (1.4) versus 2.2 (1.4) years. The use of CGM increased from 0% to 98% and the use of an insulin pump from 40% in 2008 to 82% (p < 0.01)in 2018.Mean HbA1c was 58 mmol/mol (7.4%) in 2008 and 50 mmol/mol (6.7%) in 2018 (p < 0.01). The frequency of overweight and obesity was the same in 2008 and 2018(26% vs. 29%). Conclusion: During this decade, usage of CGM and insulin pump increased and HbA1c decreased. However, HbA1c remained higher than the physiological level and thus continued to represent a cardiovascular risk, especially in combination with overweight or obesity. The frequency of overweight and obesity remained unchanged. © 2021 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- HbA1c
- overweight
- preschool
- type 1 diabetes
- HbA1c
Publication and Content Type
- ref (subject category)
- art (subject category)
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