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  • Nilsson Sommar, JohanUmeå universitet,Avdelningen för hållbar hälsa (author)

Long-term exposure to particulate air pollution and black carbon in relation to natural and cause-specific mortality: a multicohort study in Sweden

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-09-08
  • BMJ,2021

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/309279
  • https://gup.ub.gu.se/publication/309279URI
  • https://doi.org/10.1136/bmjopen-2020-046040DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187743URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-198219URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:147677276URI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Objectives To estimate concentration-response relationships for particulate matter (PM) and black carbon (BC) in relation to mortality in cohorts from three Swedish cities with comparatively low pollutant levels. Setting Cohorts from Gothenburg, Stockholm and Umea, Sweden. Design High-resolution dispersion models were used to estimate annual mean concentrations of PM with aerodynamic diameter <= 10 mu m (PM10) and <= 2.5 mu m (PM2.5), and BC, at individual addresses during each year of follow-up, 1990-2011. Moving averages were calculated for the time windows 1-5 years (lag1-5) and 6-10 years (lag6-10) preceding the outcome. Cause-specific mortality data were obtained from the national cause of death registry. Cohort-specific HRs were estimated using Cox regression models and then meta-analysed including a random effect of cohort. Participants During the study period, 7 340 cases of natural mortality, 2 755 cases of cardiovascular disease (CVD) mortality and 817 cases of respiratory and lung cancer mortality were observed among in total 68 679 individuals and 689 813 person-years of follow-up. Results Both PM10 (range: 6.3-41.9 mu g/m(3)) and BC (range: 0.2-6.8 mu g/m(3)) were associated with natural mortality showing 17% (95% CI 6% to 31%) and 9% (95% CI 0% to 18%) increased risks per 10 mu g/m(3) and 1 mu g/m(3) of lag1-5 exposure, respectively. For PM2.5 (range: 4.0-22.4 mu g/m(3)), the estimated increase was 13% per 5 mu g/m(3), but less precise (95% CI -9% to 40%). Estimates for CVD mortality appeared higher for both PM10 and PM2.5. No association was observed with respiratory mortality. Conclusion The results support an effect of long-term air pollution on natural mortality and mortality in CVD with high relative risks also at low exposure levels. These findings are relevant for future decisions concerning air quality policies.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Andersson, Eva M.,1968Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden(Swepub:gu)xaevaq (author)
  • Andersson, N.Karolinska Institutet (author)
  • Sällsten, Gerd,1952Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden(Swepub:gu)xsalge (author)
  • Stockfelt, Leo,1981Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Danderyd Hospital, Stockholm, Sweden(Swepub:gu)xstole (author)
  • Ljungman, P. L. S.Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden (author)
  • Segersson, D.Swedish Meteorological and Hydrological Institute, Norrkoping, Sweden (author)
  • Eneroth, K.Karolinska Institutet (author)
  • Gidhagen, L.Swedish Meteorological and Hydrological Institute, Norrkoping, Sweden (author)
  • Molnár, Peter,1967Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden(Swepub:gu)xmolnp (author)
  • Wennberg, Patrik,1972-Umeå universitet,Allmänmedicin(Swepub:umu)pawe0002 (author)
  • Rosengren, Annika,1951Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Goteborg, Sweden(Swepub:gu)xrosan (author)
  • Rizzuto, D.Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Gerontology Research Centrum, Sweden (author)
  • Leander, K.Karolinska Institutet (author)
  • Lager, A.Karolinska Institutet (author)
  • Magnusson, P. K. E. (author)
  • Johansson, ChristerStockholms universitet,Institutionen för miljövetenskap,Environment and Health Administration, Sweden(Swepub:su)chjoh (author)
  • Barregård, Lars,1948Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden(Swepub:gu)xbarrl (author)
  • Bellander, T.Karolinska Institutet (author)
  • Pershagen, G.Karolinska Institutet (author)
  • Forsberg, Bertil,professor,1956-Umeå universitet,Avdelningen för hållbar hälsa(Swepub:umu)befo0001 (author)
  • Umeå universitetAvdelningen för hållbar hälsa (creator_code:org_t)

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  • In:Bmj Open: BMJ11:92044-6055

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