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  • Karlsson Sundbaum, JohannaLuleå University of Technology,Luleå tekniska universitet,Hälsa, medicin och rehabilitering,Luleå Univ Technol, Dept Hlth Educ & Technol, S-97187 Luleå, Sweden. (författare)

Uncontrolled asthma predicts severe COVID-19: a report from the Swedish National Airway Register.

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • 2022-04-18
  • SAGE Publications,2022

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/315807
  • https://gup.ub.gu.se/publication/315807URI
  • https://doi.org/10.1177/17534666221091183DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-194360URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-90388URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-473569URI
  • https://lup.lub.lu.se/record/99ffbc81-522f-4eee-912c-4c2db8f10e9bURI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:149328140URI

Kompletterande språkuppgifter

  • Språk:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Validerad;2022;Nivå 2;2022-05-01 (joosat);
  • Severe asthma increases the risk of severe COVID-19 outcomes such as hospitalization and death. However, more studies are needed to understand the association between asthma and severe COVID-19.A cohort of 150,430 adult asthma patients were identified in the Swedish National Airway Register (SNAR) from 2013 to December 2020. Data on body mass index, smoking habits, lung function, and asthma control test (ACT) were obtained from SNAR, and uncontrolled asthma was defined as ACT ⩽19. Patients with severe COVID-19 were identified following hospitalization or in death certificates based on ICD-10 codes U07.1 and U07.2. The Swedish Prescribed Drug register was used to identify comorbidities and data from Statistics Sweden for educational level. Multivariate logistic regression analyses were used to estimate associations with severe COVID-19.Severe COVID-19 was identified in 1067 patients (0.7%). Older age (OR=1.04, 95% CI=1.03-1.04), male sex (1.42, 1.25-1.61), overweight (1.56, 1.27-1.91), obesity (2.12, 1.73-2.60), high-dose inhaled corticosteroids in combination with long-acting β-agonists (1.40, 1.22-1.60), dispensed oral corticosteroids ⩾2 (1.48, 1.25-1.75), uncontrolled asthma (1.64, 1.35-2.00), cardiovascular disease (1.20, 1.03-1.40), depression (1.47, 1.28-1.68), and diabetes (1.52, 1.29-1.78) were associated with severe COVID-19, while current smoking was inversely associated (0.63, 0.47-0.85). When comparing patients who died from COVID-19 with those discharged alive from hospital until 31 December 2020, older age, male sex, and current smoking were associated with COVID-19 death.Patients with uncontrolled asthma and high disease burden, including increased asthma medication intensity, should be identified as risk patients for severe COVID-19. Furthermore, current smoking is strongly associated with COVID-19 death in asthma.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Konradsen, Jon RKarolinska Institutet,Karolinska Institute (författare)
  • Vanfleteren, Lowie E G WGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, COPD Ctr, Dept Resp Med & Allergol, Gothenburg, Sweden.;Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden.(Swepub:gu)xvanlo (författare)
  • Axelsson Fisk, StenLund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Ystad Hospital(Swepub:lu)st3813ax (författare)
  • Pedroletti, ChristopheUppsala University,Uppsala universitet,Institutionen för kvinnors och barns hälsa (författare)
  • Sjöö, YvonneThe Swedish National Airway Register, Gothenburg, Sweden,Swedish Natl Airway Register, Gothenburg, Sweden. (författare)
  • Syk, JörgenKarolinska Institutet,Uppsala University,Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Acad Primary Hlth Care Ctr, Stockholm, Sweden; Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden(Swepub:uu)jorsy873 (författare)
  • Sterner, ThereseLund University,Lunds universitet,Dermatologi,Forskargrupper vid Lunds universitet,Dermatology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-tse (författare)
  • Lindberg, AnneUmeå University,Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Umeå University, Devision of Medicine/ The OLIN- unit, Umeå University, Umeå, Sweden,Umeå Univ, Devis Med OLIN Unit, Dept Publ Hlth & Clin Med, Umeå, Sweden.(Swepub:umu)anelig02 (författare)
  • Tunsäter, AlfLund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)med-atr (författare)
  • Nyberg, Fredrik,1961University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Sch Publ Hlth & Community Med, Inst Med, Gothenburg, Sweden.(Swepub:gu)xnybef (författare)
  • Ekberg-Jansson, AnnCOPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, COPD Ctr, Dept Resp Med & Allergol, Gothenburg, Sweden. (författare)
  • Stridsman, CarolineUmeå University,Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Umeå University, Devision of Medicine/ The OLIN- unit, Umeå University, Umeå, Sweden,Umeå Univ, Devis Med OLIN Unit, Dept Publ Hlth & Clin Med, Umeå, Sweden.(Swepub:umu)cast0052 (författare)
  • Luleå tekniska universitetHälsa, medicin och rehabilitering (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Therapeutic advances in respiratory disease: SAGE Publications161753-46661753-4658

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