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An observational an...
An observational analysis on the influence of parental allergic rhinitis, asthma and smoking on exhaled nitric oxide in offspring
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- Zaigham, Suneela (författare)
- Uppsala University,Lund University,Lunds universitet,Uppsala universitet,Klinisk fysiologi,Department of Clinical Sciences, Cardiovascular Epidemiology, Lund University, Malmö, Sweden; Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
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- Bertelsen, R J (författare)
- Department of Clinical Science, University of Bergen, Bergen, Norway,Tartu University Clinics - Tartu, Estonia, EE,Tartu University Hospital,Lung Clinic, Tartu University Clinics, Tartu, Estonia
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- Dharmage, S C (författare)
- Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia,Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
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- Schlünssen, V (författare)
- Department of Public Health, Research Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark
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- Jögi, N O (författare)
- Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway
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- Gomez, L Palacios (författare)
- El Torrejón Health Centre. Huelva, Andalusian Health Service, Huelva, Spain
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- Holm, Mathias, 1969 (författare)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Oudin, A. (författare)
- Umeå universitet,Umeå University,Avdelningen för hållbar hälsa
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- Abramson, M J (författare)
- Uppsala University,School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia,Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway,Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden
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- Sigsgaard, T (författare)
- Department of Public Health, Research Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark
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Jõgi, R (författare)
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Svanes, C (författare)
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- Olin, A C (författare)
- University of Gothenburg,Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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- Forsberg, Bertil, professor, 1956- (författare)
- Umeå universitet,Umeå University,Avdelningen för hållbar hälsa
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- Janson, Christer (författare)
- Uppsala University,Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University, Uppsala, Sweden
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- Nerpin, Elisabet, 1962- (författare)
- Uppsala University,Dalarna University College,Högskolan Dalarna,Medicinsk vetenskap,Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University, Uppsala, Sweden; School of Health and Welfare, Dalarna University, Falun, Sweden
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Johannessen, A (författare)
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- Malinovschi, Andrei, 1978- (författare)
- Uppsala universitet,Klinisk fysiologi
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(creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: Nitric oxide. - : Elsevier. - 1089-8603 .- 1089-8611. ; 149, s. 60-66
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Parental allergic diseases and smoking influence respiratory disease in the offspring but it is not known whether they influence fractional exhaled nitric oxide (FeNO) in the offspring. We investigated whether parental allergic diseases, parental smoking and FeNO levels in parents were associated with FeNO levels in their offspring.METHODS: We studied 609 offspring aged 16-47 years from the Respiratory Health in Northern Europe, Spain and Australia generation (RHINESSA) study with parental information from the Respiratory Health in Northern Europe (RHINE) III study and the European Community Respiratory Health Survey (ECRHS) III. Linear regression models were used to assess the association between offspring FeNO and parental FeNO, allergic rhinitis, asthma and smoking, while adjusting for potential confounding factors.RESULTS: Parental allergic rhinitis was significantly associated with higher FeNO in the offspring, both on the paternal and maternal side (percent change: 20.3 % [95%CI 5.0-37.7], p = 0.008, and 13.8 % [0.4-28.9], p = 0.043, respectively). Parental allergic rhinitis with asthma in any parent was also significantly associated with higher offspring FeNO (16.2 % [0.9-33.9], p = 0.037). However, parental asthma alone and smoking were not associated with offspring FeNO. Parental FeNO was not associated with offspring FeNO after full adjustments for offspring and parental factors.CONCLUSIONS: Parental allergic rhinitis but not parental asthma was associated with higher levels of FeNO in offspring. These findings suggest that parental allergic rhinitis status should be considered when interpreting FeNO levels in offspring beyond childhood.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Allergic rhinitis
- Asthma
- FeNO
- Offspring
- Parental allergic disease
- Lungmedicin
- Lung Medicine
- Clinical Physiology
- Klinisk fysiologi
- Allergic rhinitis
- Asthma
- FeNO
- Offspring
- Parental allergic disease
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Zaigham, Suneela
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Bertelsen, R J
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Dharmage, S C
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Schlünssen, V
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Jögi, N O
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Gomez, L Palacio ...
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visa fler...
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Holm, Mathias, 1 ...
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Oudin, A.
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Abramson, M J
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Sigsgaard, T
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Jõgi, R
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Svanes, C
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Olin, A C
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Forsberg, Bertil ...
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Janson, Christer
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Nerpin, Elisabet ...
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Johannessen, A
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Malinovschi, And ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
- Artiklar i publikationen
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Nitric oxide
- Av lärosätet
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Uppsala universitet
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Högskolan Dalarna
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Lunds universitet
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Umeå universitet
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Göteborgs universitet