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Patient-reported ou...
Patient-reported outcomes one year after positive sentinel lymph node biopsy with or without axillary lymph node dissection in the randomized SENOMAC trial
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- Appelgren, M. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Dept Mol Med & Surg, Anna Stecksens Gata 35, S-17176 Stockholm, Sweden.
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- Sackey, H. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Inst, Dept Mol Med & Surg, Anna Stecksens Gata 35, S-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Div Canc, Dept Breast Endocrine Tumors & Sarcoma, S-17164 Solna, Sweden.
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- Wengstrom, Y. (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Univ Hosp, Karolinska Comprehens Canc Ctr, S-17164 Solna, Sweden.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Nursing, S-14152 Huddinge, Sweden.
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visa fler...
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- Johansson, Karin (författare)
- Lund University,Lunds universitet,Department of Health Sciences, Lund University, Lund, Sweden,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Rehabilitering och hållbar hälsa,Forskargrupper vid Lunds universitet,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Rehabilitation and Sustainable Health,Lund University Research Groups,Lund Univ, Dept Hlth Sci, S-22100 Lund, Sweden.
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- Ahlgren, Johan (författare)
- Department of Oncology, University Hospital, Örebro, Sweden; Regional Oncology Centre, Mid-Sweden Health Care Region, Uppsala, Sweden,Univ Hosp, Dept Oncol, S-70185 Örebro, Sweden.;Midsweden Hlth Care Reg, Reg Oncol Ctr, S-75185 Uppsala, Sweden.
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- Andersson, Y. (författare)
- Uppsala University,Västmanland Hospital,Vastmanland Cty Hosp, Dept Surg, S-72189 Västerås, Sweden.;Uppsala Univ, Vastmanland Cty Hosp, Ctr Clin Res, S-72189 Västerås, Sweden.
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- Bergkvist, Leif (författare)
- Uppsala universitet,Uppsala University,Centrum för klinisk forskning, Västerås,Endokrinkirurgi
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- Frisell, J. (författare)
- Division of Cancer, Department of Breast, Endocrine Tumors and Sarcoma, Karolinska University Hospital, Solna, Sweden,Karolinska Univ Hosp, Div Canc, Dept Breast Endocrine Tumors & Sarcoma, S-17164 Solna, Sweden.
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- Lundstedt, Dan, 1970 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology,Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Univ Hosp, Sahlgrenska Acad, Inst Clin Sci,Dept Oncol, S-41345 Gothenburg, Sweden.
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- Rydén, Lisa (författare)
- Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröstcancerkirurgi,Forskargrupper vid Lunds universitet,The Liquid Biopsy och Tumörprogression i Bröstcancer,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Bröstcancerbehandling,Sektion I,Institutionen för kliniska vetenskaper, Lund,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Breast Cancer Surgery,Lund University Research Groups,The Liquid Biopsy and Tumor Progression in Breast Cancer,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Breast cancer treatment,Section I,Department of Clinical Sciences, Lund,Skåne University Hospital,Lund Univ, Dept Clin Sci Lund, Div Surg, S-22184 Lund, Sweden.;Skane Univ Hosp, Dept Surg & Gastroenterol, S-21428 Malmö, Sweden.
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- Sund, Malin (författare)
- Umeå University,Umeå universitet,Kirurgi,Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland,Umeå Univ, Dept Surg & Perioperat Sci Surg, S-70987 Umeå, Sweden.;Univ Helsinki, Dept Surg, POB 440, Helsinki, Finland.;Helsinki Univ Hosp, POB 440, Helsinki, Finland.
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- Alkner, Sara (författare)
- Lund University,Lunds universitet,Individuell Bröstcancerbehandling,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Strålterapi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Personalized Breast Cancer Treatment,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Radiation therapy,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Clin Sci Lund, Div Oncol, S-22184 Lund, Sweden.
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- Offersen, B. V. (författare)
- Department of Experimental Clinical Oncology Aarhus University Hospital, Aarhus, Denmark; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark; Danish Breast Cancer Group Center and Clinic for Late Effects, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Dept Expt Clin Oncol, DK-8200 Aarhus, Denmark.;Aarhus Univ Hosp, Dept Oncol, DK-8200 Aarhus, Denmark.;Aarhus Univ Hosp, Danish Breast Canc Grp Ctr, DK-8200 Aarhus, Denmark.;Aarhus Univ Hosp, Clin Late Effects, DK-8200 Aarhus, Denmark.
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- Tvedskov, T. F. (författare)
- Department of Breast Surgery, Rigshospitalet, Copenhagen, Denmark,Copenhagen University Hospital,Rigshosp, Dept Breast Surg, DK-2100 Copenhagen, Denmark.
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- Christiansen, P. (författare)
- Danish Breast Cancer Group Center and Clinic for Late Effects, Aarhus University Hospital, Aarhus, Denmark; Department of Plastic and Breast Surgery, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Danish Breast Canc Grp Ctr, DK-8200 Aarhus, Denmark.;Aarhus Univ Hosp, Clin Late Effects, DK-8200 Aarhus, Denmark.;Aarhus Univ Hosp, Dept Plast & Breast Surg, DK-8200 Aarhus, Denmark.
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- de Boniface, J. (författare)
- Karolinska Institutet,Karolinska Institute,Capio St. Görans Sjukhus,Karolinska Inst, Dept Mol Med & Surg, Anna Stecksens Gata 35, S-17176 Stockholm, Sweden.;Capio St Gorans Hosp, Dept Surg, S-11219 Stockholm, Sweden.
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Karolinska Institute Karolinska Inst, Dept Mol Med & Surg, Anna Stecksens Gata 35, S-17176 Stockholm, Sweden (creator_code:org_t)
- Elsevier BV, 2022
- 2022
- Engelska.
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Ingår i: Breast. - : Elsevier BV. - 0960-9776 .- 1532-3080. ; 63, s. 16-23
- Relaterad länk:
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http://www.thebreast...
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://uu.diva-port... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Introduction: This report evaluates whether health related quality of life (HRQoL) and patient-reported arm morbidity one year after axillary surgery are affected by the omission of axillary lymph node dissection (ALND). Methods: The ongoing international non-inferiority SENOMAC trial randomizes clinically node-negative breast cancer patients (T1-T3) with 1-2 sentinel lymph node (SLN) macrometastases to completion ALND or no further axillary surgery. For this analysis, the first 1181 patients enrolled in Sweden and Denmark between March 2015, and June 2019, were eligible. Data extraction from the trial database was on November 2020. This report covers the secondary outcomes of the SENOMAC trial: HRQoL and patient-reported arm morbidity. The EORTC QLQC30, EORTC QLQ-BR23 and Lymph-ICF questionnaires were completed in the early postoperative phase and at one-year follow-up. Adjusted one-year mean scores and mean differences between the groups are presented corrected for multiple testing.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Breast cancer
- Patient-reported outcome measures
- Health-related quality
- of life
- Arm morbidity
- Sentinel lymph node biopsy
- Axillary lymph node
- dissection
- quality-of-life
- breast-cancer survivors
- european-organization
- phase-iii
- health
- morbidity
- surgery
- radiotherapy
- multicenter
- reliability
- Oncology
- Obstetrics & Gynecology
- Arm morbidity
- Axillary lymph node dissection
- Health-related quality of life
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- Av författaren/redakt...
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Appelgren, M.
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Sackey, H.
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Wengstrom, Y.
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Johansson, Karin
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Ahlgren, Johan
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Andersson, Y.
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visa fler...
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Bergkvist, Leif
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Frisell, J.
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Lundstedt, Dan, ...
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Rydén, Lisa
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Sund, Malin
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Alkner, Sara
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Offersen, B. V.
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Tvedskov, T. F.
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Christiansen, P.
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de Boniface, J.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
- Artiklar i publikationen
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Breast
- Av lärosätet
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Göteborgs universitet
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Umeå universitet
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Lunds universitet
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Uppsala universitet
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Karolinska Institutet