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Prevalence of sensi...
Prevalence of sensitization to molecular food allergens in Europe: A systematic review.
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- Lisik, Daniil (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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- Ioannidou, Athina (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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Spolidoro, Giulia (författare)
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- Ali, Mohamed Mustafa (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Nyassi, Sungkutu (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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- Amera, Yohannes Tesfaye (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Rovner, Graciela (författare)
- Karolinska Institutet
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Khaleva, Ekaterina (författare)
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Venter, Carina (författare)
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van Ree, Ronald (författare)
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Worm, Margitta (författare)
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Vlieg-Boerstra, Berber (författare)
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Sheikh, Aziz (författare)
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Muraro, Antonella (författare)
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Roberts, Graham (författare)
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- Nwaru, Bright I, 1978 (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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(creator_code:org_t)
- 2022-07-06
- 2022
- Engelska.
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Ingår i: Clinical and translational allergy. - : Wiley. - 2045-7022. ; 12:7
- Relaterad länk:
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Recent reports indicate that the prevalence of food allergy is increasing, but accurate estimates remain a challenge due to cross-reactivity and limited use of precise diagnostic methods. Molecular allergy diagnostics, in which sensitization to individual molecular allergens is measured, is emerging as a promising tool for evaluation of sensitization profiles. In this systematic review, we summarized estimates of prevalence of sensitization to molecular food allergens in the general population in Europe.Following a protocol prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO; reference CRD42021266657), we searched seven databases with no restrictions on publication date or language. Two reviewers independently screened the literature, extracted data, and appraised the risk of bias in the included studies. The findings were synthesized narratively.From 4776 de-duplicated records, five studies, with low to moderate overall risk of bias, were included. Forty-six molecular allergens from 18 foods were investigated. Overall, the prevalence of sensitization was low, particularly for major allergens, and non-existent for 10 molecular allergens (0% [95% CI 0-0.8]). The highest prevalence was seen for PR-10 proteins, such as Cor a 1.04 (13.6% [95% CI 10.9-16.9]).Available data, primarily from North-western Europe, indicate that sensitization to molecular food allergens is overall low. The highest estimates were found for cross-reactive PR-10 proteins. There were not enough studies to discern regional differences or perform meta-analysis, highlighting the need for more population-representative studies in order to elucidate patterns of sensitization to molecular food allergens in Europe.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- epidemiology
- food allergy
- molecular allergen
- sensitization
- systematic review
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Lisik, Daniil
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Ioannidou, Athin ...
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Spolidoro, Giuli ...
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Ali, Mohamed Mus ...
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Nyassi, Sungkutu
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Amera, Yohannes ...
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visa fler...
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Rovner, Graciela
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Khaleva, Ekateri ...
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Venter, Carina
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van Ree, Ronald
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Worm, Margitta
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Vlieg-Boerstra, ...
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Sheikh, Aziz
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Muraro, Antonell ...
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Roberts, Graham
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Nwaru, Bright I, ...
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Clinical and tra ...
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Göteborgs universitet
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Karolinska Institutet