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Reconstructive surg...
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Derks, Jan,1977Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2
(författare)
Reconstructive surgical therapy of peri-implantitis: A multicenter randomized controlled clinical trial
- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
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LIBRIS-ID:oai:gup.ub.gu.se/317613
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https://gup.ub.gu.se/publication/317613URI
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https://doi.org/10.1111/clr.13972DOI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Objective To evaluate the potential benefit of the use of a bone substitute material in the reconstructive surgical therapy of peri-implantitis. Methods In this multicenter randomized clinical trial, 138 patients (147 implants) with peri-implantitis were treated surgically, randomized by coin toss to either a control (access flap surgery) or a test group (reconstructive surgery using bone substitute material). Clinical assessments, including probing pocket depth (PPD), bleeding and suppuration on probing (BOP & SOP) as well as soft tissue recession (REC), were recorded at baseline, 6 and 12 months. Marginal bone levels (MBL), measured on intra-oral radiographs, and patient-reported outcomes (PROs) were recorded at baseline and 12 months. No blinding to group allocation was performed. The primary outcome at 12 months was a composite measure including (i) implant not lost, (ii) absence of BOP/SOP at all aspects, (iii) PPD <= 5 mm at all aspects and (iv) <= 1 mm recession of mucosal margin on the buccal aspect of the implant. Secondary outcomes included (i) changes of MBL, (ii) changes of PPD, BOP%, and buccal KM, (iii) buccal REC and (iv) patient-reported outcomes. Results During follow-up, four implants (one in the test group, three in the control group) in four patients were removed due to disease progression. At 12 months, a total of 69 implants in the test and 68 implants in the control group were examined. Thus, 16.4% and 13.5% of implants in the test and control group, respectively, met all predefined criteria of the composite outcome. PPD reduction and MBL gain were 3.7 mm and about 1.0 mm in both groups. Reduction in mean BOP% varied between 45% (test) and 50% (control), without significant differences between groups. Buccal REC was less pronounced in the test group (M = 0.7, SD = 0.9 mm) when compared to controls (M = 1.1, SD = 1.5 mm). PROs were favorable in both groups without significant differences. One case of allergic reaction to the antibiotic therapy was recorded. No other adverse events were noted. Conclusions Surgical therapy of peri-implantitis effectively improved the clinical and radiographic status at 12 months. While the use of a bone substitute material did not improve reductions of PPD and BOP, buccal REC was less pronounced in the test group. Patient satisfaction was high in both groups.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ortiz-Vigon, A.
(författare)
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Guerrero, A.
(författare)
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Donati, Mauro,1966Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xdonma
(författare)
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Bressan, E.
(författare)
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Ghensi, P.
(författare)
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Schaller, D.
(författare)
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Tomasi, Cristiano,1964Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xtomcr
(författare)
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Karlsson, Karolina,1975Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xkkaro
(författare)
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Abrahamsson, Ingemar,1953Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xabrin
(författare)
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Ichioka, YukiGothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xiyuki
(författare)
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Dionigi, CarlottaGothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xcadio
(författare)
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Regidor, E.
(författare)
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Berglundh, Tord,1954Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xbetor
(författare)
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Göteborgs universitetInstitutionen för odontologi, sektion 2
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Clinical Oral Implants Research: Wiley33:9, s. 921-9440905-71611600-0501
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Derks, Jan, 1977
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Ortiz-Vigon, A.
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Guerrero, A.
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Donati, Mauro, 1 ...
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Bressan, E.
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Ghensi, P.
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visa fler...
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Schaller, D.
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Tomasi, Cristian ...
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Karlsson, Karoli ...
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Abrahamsson, Ing ...
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Ichioka, Yuki
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Dionigi, Carlott ...
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Regidor, E.
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Berglundh, Tord, ...
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Clinical Oral Im ...
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Göteborgs universitet