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World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders - Version 3. Part II: OCD and PTSD

Bandelow, B. (författare)
Univ Gottingen, Dept Psychiat & Psychotherapy, Gottingen, Germany.
Allgulander, Christer (författare)
Uppsala universitet,Psykiatri
Baldwin, D. S. (författare)
Univ Southampton, Fac Med, Southampton, Hants, England.,Univ Med Ctr, Afdeling Psychiat, Amsterdam, Netherlands.
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Costa, D. L. D. (författare)
Univ Sao Paulo, Hosp Clin, Sch Med, Dept & Inst Psychiat, Sao Paulo, Brazil.,Singapore Gen Hosp, Dept Psychiat, Singapore, Singapore.
Denys, D. (författare)
Dilbaz, N. (författare)
Uskudar Univ, Tip Fak Psikiyatri ABD Istanbul, Istanbul, Turkey.
Domschke, K. (författare)
Univ Freiburg, Med Ctr, Fac Med, Dept Psychiat & Psychotherapy, Freiburg, Germany.
Hollander, E. (författare)
Albert Einstein Coll Med, New York, NY USA.
Kasper, S. (författare)
Univ Vienna, Clin Div Gen Psychiat Med, Vienna, Austria.
Moller, H. J. (författare)
Univ Munich, Dept Psychiat & Psychotherapy, Munich, Germany.,Treatment Ctr Anxiety & Depress, Zurich, Switzerland.
Eriksson, Elias, 1956 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi,Institute of Neuroscience and Physiology, Department of Pharmacology,Univ Gothenburg, Dept Pharmacol, Gothenburg, Sweden.,Univ Fed Rio de Janeiro, Inst Psychiat, Rio De Janeiro, Brazil.
Fineberg, N. A. (författare)
Univ Hertfordshire, Sch Life & Med Sci, Hatfield, Herts, England.
Haettenschwiler, J. (författare)
Kaiya, H. (författare)
Kyoto Prefactual Med Coll, Dept Psychiat, Kyoto, Japan.
Karavaeva, T. (författare)
St Petersburg State Univ, Fed State Budgetary Inst Higher Educ, Minist Hlth, VM Bekhterev Natl Med Res Ctr Psychiat & Neurol, St Petersburg, Russia.;St Petersburg State Univ, Fed State Budgetary Inst Higher Educ, St Petersburg, Russia.
Katzman, M. A. (författare)
START Clin, Toronto, ON, Canada.;Adler Grad Profess Sch Toronto, Toronto, ON, Canada.;Northern Ontario Sch Med Thunder Bay, Dept Psychiat, Thunder Bay, ON, Canada.;Lakehead Univ, Dept Psychol, Thunder Bay, ON, Canada.
Kim, Y. K. (författare)
Korea Univ, Coll Med, Dept Psychiat, Seoul, South Korea.
Inoue, T. (författare)
Tokyo Med Univ, Dept Psychiat, Tokyo, Japan.
Lim, L. (författare)
Masdrakis, V. (författare)
Natl & Kapodistrian Univ Athens, Eginit Hosp, Med Sch, Dept Psychiat 1, Athens, Greece.
Menchon, J. M. (författare)
Univ Barcelona, Bellvitge Univ Hosp IDIBELL, Cibersam, Dept Psychiat, Barcelona, Spain.
Miguel, E. C. (författare)
Univ Sao Paulo, Fac Med, Dept Psychiat, Sao Paulo, SP, Brazil.
Nardi, A. E. (författare)
Pallanti, S. (författare)
Univ Florence, Florence, Italy.
Perna, G. (författare)
Humanitas Univ Pieve Emanuele, Dept Biol Sci, Milan, Italy.
Rujescu, D. (författare)
Univ Vienna, Clin Div Gen Psychiat Med, Vienna, Austria.
Starcevic, V. (författare)
Univ Sydney, Sydney Med Sch, Nepean Clin Sch, Fac Med & Hlth, Sydney, NSW, Australia.
Stein, D. J. (författare)
Univ Cape Town, Dept Psychiat, SA MRC Unit Risk & Resilience Mental Disorders, Cape Town, South Africa.;Univ Cape Town, Neurosci Inst, Cape Town, South Africa.
Tsai, S. J. (författare)
Taipei Vet Gen Hosp, Dept Psychiat, Taipei, Taiwan.
Van Ameringen, M. (författare)
McMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada.
Vasileva, A. (författare)
II Mechnikov North Western State Med Univ, Minist Hlth, VM Bekhterev Natl Med Res Ctr Psychiat & Neurol, St Petersburg, Russia.
Wang, Z. (författare)
Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Shanghai, Peoples R China.
Zohar, J. (författare)
Chaim Sheba Med Ctr, Tel Aviv, Israel.
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Univ Gottingen, Dept Psychiat & Psychotherapy, Gottingen, Germany Psykiatri (creator_code:org_t)
2022-07-28
2023
Engelska.
Ingår i: World Journal of Biological Psychiatry. - : Informa UK Limited. - 1562-2975 .- 1814-1412. ; 24:2, s. 118-134
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Aim: This is the third version of the guideline of the World Federation of Societies of Biological Psychiatry (WFSBP) Task Force for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Posttraumatic Stress Disorders which was published in 2002 and revised in 2008. Method: A consensus panel of 34 international experts representing 22 countries developed recommendations based on efficacy and acceptability of the treatments. In this version, not only medications but also psychotherapies and other non-pharmacological interventions were evaluated, applying the same rigorous methods that are standard for the assessment of medication treatments. Result: The present paper (Part II) contains recommendations based on published randomised controlled trials (RCTs) for the treatment of OCD (n = 291) and PTSD (n = 234) in children, adolescents, and adults. The accompanying paper (Part I) contains the recommendations for the treatment of anxiety disorders. For OCD, first-line treatments are selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioural therapy (CBT). Internet-CBT was also superior to active controls. Several second-line medications are available, including clomipramine. For treatment-resistant cases, several options are available, including augmentation of SSRI treatment with antipsychotics and other drugs. Other non-pharmacological treatments, including repetitive transcranial magnetic stimulation (rTMS), deep brain stimulation (DBS) and others were also evaluated. For PTSD, SSRIs and the SNRI venlafaxine are first-line treatments. CBT is the psychotherapy modality with the best body of evidence. For treatment-unresponsive patients, augmentation of SSRI treatment with antipsychotics may be an option. Conclusion: OCD and PTSD can be effectively treated with CBT and medications.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Obsessive-compulsive disorder
posttraumatic stress disorder
treatment
children
guideline
transcranial magnetic stimulation
serotonin reuptake inhibitors
eye-movement desensitization
high-dose escitalopram
long-term
treatment
double-blind
20 mg
placebo
fluoxetine
sertraline
Psychiatry
Obsessive-compulsive disorder

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