Medication use in populations exposed to the 2010 Eyjafjallajökull eruption: an interrupted time series analysis

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Guðmundsdóttir, R. B. (author)

Medication use in populations exposed to the 2010 Eyjafjallajökull eruption: an interrupted time series analysis

Article/chapterEnglish2022

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2022-05-09
BMJ,2022

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LIBRIS-ID:oai:gup.ub.gu.se/320836
https://gup.ub.gu.se/publication/320836URI
https://doi.org/10.1136/bmjopen-2021-059375DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:149644220URI

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Language:English

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Subject category:art swepub-publicationtype

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OBJECTIVES: To assess the trends in medication use indicative of physical and psychological morbidity following the 2010 volcanic eruption in Eyjafjallajökull immediately after and during a 3-year period following the eruption. DESIGN: Population-based register study. SETTING: Eyjafjallajökull eruption in Iceland, 2007-2013. PARTICIPANTS: All residents in Iceland who received at least one medication dispensing were identified. Residents of exposed areas were classified into exposure groups (individual-level data) and residents in other parts of Iceland were included as a non-exposed group (aggregated data). INTERVENTION/EXPOSURE: Eyjafjallajökull erupted on 14 April 2010 and continued for 39 days, producing heavy ash fall in South Iceland. MAIN OUTCOME MEASURES: Using interrupted time series analysis, we examined annual and quarterly changes in medicine use, measured as number of dispensed defined daily dose (DDD) per 1000 individuals. We calculated the level shift (immediate change) and change in slope from pre-eruption to post-eruption (long-term change) in medication dispensing. RESULTS: Among exposed residents, there was a 6% decrease (95%CI -7% to -4%) in the annual number of dispensed DDDs 1-year post-eruption in the overall medication class, including analgesics (-5%, 95%CI -6% to -3%), hypnotics and sedatives (-9%, 95%CI -11% to -7%) and respiratory medications (-7%, 95%CI -9% to -5%; -8%, 95%CI -11% to -4%). Simultaneously, there was a 9% decrease (95%CI -14% to -4%) in the overall medication class among non-exposed residents. Moreover, among exposed residents, we observed change in slope of -4% (95%CI -7% to -1%) in the overall medication class, including for analgesics (-6%, 95%CI -8% to -3%) and other respiratory drugs (-10%, 95%CI -16% to -4%). CONCLUSION: Our findings indicate that the eruption did not lead to increases in medication dispensing among residents of exposed areas, rather decreases for some medicine classes. The results should be interpreted with caution since the content of each eruption differs.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
epidemiology
mental health
public health

Added entries (persons, corporate bodies, meetings, titles ...)

Jónsson, B. G. G. (author)
Valdimarsdottir, U.Karolinska Institutet (author)
Carlsen, Hanne KrageGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine(Swepub:gu)xkraha (author)
Hlodversdottir, H. (author)
Song, H. (author)
Thordardottir, E. B. (author)
Pétursdóttir, G. (author)
Briem, H. (author)
Gislason, T. (author)
Gudnason, T. (author)
Thorsteinsson, T. (author)
Zoega, H. (author)
Hauksdóttir, A. (author)
Karolinska InstitutetInstitutionen för medicin, avdelningen för samhällsmedicin och folkhälsa (creator_code:org_t)

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In:Bmj Open: BMJ12:52044-6055

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