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(AMNE:(MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reumatologi och inflammation)) srt2:(2020-2024)
 

Search: (AMNE:(MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reumatologi och inflammation)) srt2:(2020-2024) > Systemic inflammati...

Systemic inflammation and risk of multiple sclerosis – A presymptomatic case-control study

Grut, Viktor (author)
Umeå University,Umeå universitet,Neurovetenskaper,Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden
Biström, Martin, 1982- (author)
Umeå University,Umeå universitet,Neurovetenskaper,Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden
Salzer, Jonatan (author)
Umeå University,Umeå universitet,Neurovetenskaper,Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden
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Stridh, Pernilla (author)
Karolinska Institute,Karolinska Institutet,Karolinska University Hospital
Lindam, Anna, PhD, 1978- (author)
Umeå University,Umeå universitet,Allmänmedicin,Department of Public Health and Clinical Medicine, Unit of Research, Education and Development Östersund Hospital, Umeå University, Umeå, Sweden
Alonso-Magdalena, Lucia (author)
Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
Andersen, Oluf, 1941 (author)
University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Jons, Daniel, 1974 (author)
University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Gunnarsson, Martin, 1973- (author)
Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Neurology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
Vrethem, Magnus, 1955- (author)
Linköping University,Linköpings universitet,Medicinska fakulteten,Avdelningen för neurobiologi,Region Östergötland, Neurologiska kliniken i Linköping
Hultdin, Johan (author)
Umeå University,Umeå universitet,Klinisk kemi,Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden
Sundström, Peter (author)
Umeå University,Umeå universitet,Neurovetenskaper,Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden
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 (creator_code:org_t)
2022-11-22
2022
English.
In: Multiple Sclerosis Journal - Experimental, Translational and Clinical. - : SAGE Publications. - 2055-2173. ; 8:4
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Background: C-reactive protein (CRP) is a marker of systemic inflammation. Increased levels of CRP in young persons have been suggested to decrease the risk of multiple sclerosis (MS). Objectives: To assess CRP as a risk factor for MS. Methods: Levels of CRP were measured with a high-sensitive immunoassay in biobank samples from 837 individuals who later developed MS and 984 matched controls. The risk of developing MS was analysed by conditional logistic regression on z-scored CRP values. Results: Levels of CRP were not associated with MS risk. Conclusions: We found no association between CRP levels and risk of MS development.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)

Keyword

C-reactive protein
Case-control studies
multiple sclerosis
systemic inflammation
C-reactive protein

Publication and Content Type

ref (subject category)
art (subject category)

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