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Satisfaction with S...
Satisfaction with Social Roles and Physical Function in Immune-mediated Inflammatory Diseases: A Cross-Sectional Study
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Spagnuolo, R. (författare)
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Iaquinta, F. S. (författare)
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Mauro, D. (författare)
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Pantano, I. (författare)
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Dastoli, S. (författare)
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Naty, S. (författare)
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Cosco, C. (författare)
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- Mancina, Rosellina Margherita (författare)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Wallenberg Laboratory,Institute of Medicine, Department of Molecular and Clinical Medicine
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Iacono, D. (författare)
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Gaggiano, E. (författare)
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Ruggiero, A. (författare)
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Nistico, S. P. (författare)
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Ciccia, F. (författare)
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Grembiale, R. D. (författare)
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Patrizia, D. (författare)
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(creator_code:org_t)
- Bentham Science Publishers Ltd. 2022
- 2022
- Engelska.
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Ingår i: Reviews on Recent Clinical Trials. - : Bentham Science Publishers Ltd.. - 1574-8871. ; 17:3, s. 177-186
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Background: Although mood disorders have been well characterized by immune-mediated inflammatory diseases, physical function and satisfaction with social roles have not yet been defined as independent domains. Objective: The study aims to assess satisfaction with social roles and physical function alterations in a population with immune-mediated inflammatory diseases and identify associated characteristics. Methods: Physical function and social role satisfaction were evaluated through the Patient-reported Outcomes Measurement System. Besides comparison between groups, univariate and multivariable logistic regression analyses were performed to identify independent predictors. Results: Two hundred sixty-five patients with immune-mediated inflammatory diseases and 206 controls were recruited. Compared to controls, patients with inflammatory bowel diseases had impaired physical function (p<0.001), while patients with inflammatory arthritis reported impairment in both domains (p<0.001, each). In the univariate logistic regression, gender, high school educational level, physical activity, and occupation were positively associated with physical function and social role satisfaction (pp=0.001; pp=0.001 and pp=0.012; p=0.008; p=0.004, respectively). Active disease and steroids were inversely associated with physical function and social roles satisfaction (p=0.033; p=0.022 and p=0.002; p=0.038, respectively). Further associations were found between age and physical function (p=0.002) and biological treatment and ESR with social roles satisfaction (pp=0.043; respectively). In the multivariable regression, gender was found to be associated with physical function (p<0.001) and social roles satisfaction (p=0.003). Negatively associated factors were biological treatment for satisfaction with social roles (p<0.001) and steroids for physical function (p=0.021), and social roles satisfaction (p=0.018). Conclusion: Immune-mediated inflammatory diseases determine alterations in physical function and social life satisfaction. Gender and treatment are independently associated factors. Patient-reported outcomes should be considered in clinical management to define patients' real needs.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Nyckelord
- Immune-mediated inflammatory diseases
- PROMIS
- inflammatory bowel
- disease
- inflammatory arthritis
- psoriasis
- physical function
- social
- satisfaction
- quality-of-life
- patient-reported outcomes
- classification criteria
- ankylosing-spondylitis
- rheumatoid-arthritis
- clinical-trial
- bowel-disease
- information
- maintenance
- perceptions
- Pharmacology & Pharmacy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Spagnuolo, R.
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Iaquinta, F. S.
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Mauro, D.
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Pantano, I.
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Dastoli, S.
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Naty, S.
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visa fler...
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Cosco, C.
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Mancina, Roselli ...
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Iacono, D.
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Gaggiano, E.
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Ruggiero, A.
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Nistico, S. P.
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Ciccia, F.
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Grembiale, R. D.
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Patrizia, D.
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visa färre...
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Göteborgs universitet