Is sibship composition a risk factor for childhood asthma? Systematic review and meta-analysis

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:gup.ub.gu.se/324906" > Is sibship composit...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Lisik, DaniilGothenburg University,Göteborgs universitet,Krefting Research Centre (author)

Is sibship composition a risk factor for childhood asthma? Systematic review and meta-analysis

Article/chapterEnglish2023

Publisher, publication year, extent ...

2023

Numbers

LIBRIS-ID:oai:gup.ub.gu.se/324906
https://gup.ub.gu.se/publication/324906URI
https://doi.org/10.1007/s12519-023-00706-wDOI

Supplementary language notes

Language:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Following the "hygiene hypothesis", the role of sibship composition in asthma and wheezing has been extensively studied, but the findings are inconsistent. For the first time, this systematic review and meta-analysis synthesized evidences from studies investigating the association of sibship size and birth order with risk of asthma and wheezing.Fifteen databases were searched to identify eligible studies. Study selection and data extraction were performed independently by pairs of reviewers. Meta-analysis with robust variance estimation (RVE) was used to produce pooled risk ratio (RR) effect estimates from comparable numerical data.From 17,466 identified records, 158 reports of 134 studies (>3 million subjects) were included. Any wheezing in the last≤1.5years occurred more frequently in infants with≥1 sibling [pooled RR 1.10, 95% confidence interval (CI) 1.02-1.19] and≥1 older sibling (pooled RR 1.16, 95% CI 1.04-1.29). The pooled effect sizes for asthma were overall statistically nonsignificant, although having≥1 older sibling was marginally protective for subjects aged≥6years (pooled RR 0.93, 95% CI 0.88-0.99). The effect estimates weakened in studies published after 2000 compared with earlier studies.Being second-born or later and having at least one sibling is associated with a slightly increased risk of temporary wheezing in infancy. In contrast, being second-born or later is associated with marginal protection against asthma. These associations appear to have weakened since the turn of the millennium, possibly due to lifestyle changes and socioeconomic development. Video Abstract.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Lungmedicin och allergi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Respiratory Medicine and Allergy hsv//eng
NATURVETENSKAP Matematik Sannolikhetsteori och statistik hsv//swe
NATURAL SCIENCES Mathematics Probability Theory and Statistics hsv//eng
Asthma; Hygiene hypothesis; Respiratory sounds; Siblings; Systematic review

Added entries (persons, corporate bodies, meetings, titles ...)

Ermis, Özuygur,1991Gothenburg University,Göteborgs universitet,Krefting Research Centre(Swepub:gu)xozusa (author)
Ioannidou, AthinaGothenburg University,Göteborgs universitet,Krefting Research Centre (author)
Milani, Gregorio Paolo (author)
Nyassi, SungkutuGothenburg University,Göteborgs universitet,Krefting Research Centre (author)
Spolidoro, Giulia Carla Immacolata (author)
Kankaanranta, Hannu,1967Gothenburg University,Göteborgs universitet,Krefting Research Centre(Swepub:gu)xkankh (author)
Goksör, Emma,1974Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics(Swepub:gu)xgokem (author)
Wennergren, Göran,1947Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Krefting Research Centre,Institute of Clinical Sciences, Department of Pediatrics(Swepub:gu)xwengo (author)
Nwaru, Bright I,1978Gothenburg University,Göteborgs universitet,Krefting Research Centre,Wallenberg Centre for Molecular and Translational Medicine(Swepub:gu)xnwabr (author)
Göteborgs universitetKrefting Research Centre (creator_code:org_t)

Related titles

In:World journal of pediatrics : WJP19:12, s. 1127-381867-0687

Internet link

Find in a library

World journal of pediatrics : WJP (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Lisik, Daniil; Ermis, Özuygur, ...; Ioannidou, Athin ...; Milani, Gregorio ...; Nyassi, Sungkutu; Spolidoro, Giuli ...; show more...; Kankaanranta, Ha ...; Goksör, Emma, 19 ...; Wennergren, Göra ...; Nwaru, Bright I, ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Respiratory Medi ...

NATURAL SCIENCES: NATURAL SCIENCES; and Mathematics; and Probability Theo ...

Articles in the publication: World journal of ...

By the university: University of Gothenburg

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se