Search: WFRF:(Taflin Helena) >
The Resection Rate ...
The Resection Rate of Synchronously Detected Liver and Lung Metastasis from Colorectal Cancer Is Low-A National Registry-Based Study
-
- Engstrand, J. (author)
- Karolinska Institutet
-
- Taflin, Helena (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrens Univ Hosp, Sahlgrenska Acad Univ Gothenburg, Inst Clin Sci, Dept Surg, S-41345 Gothenburg, Sweden.
-
- Rystedt, Jenny Lundmark (author)
- Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Forskargrupper vid Lunds universitet,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Surgery,Lund University Research Groups,Skåne University Hospital
-
show more...
-
- Hemmingsson, Oskar, 1975- (author)
- Umeå University,Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Umeå Univ, Dept Surg & Perioperat Sci, S-90187 Umeå, Sweden.;Umeå Univ, Wallenberg Ctr Mol Med, S-90187 Umeå, Sweden.
-
- Urdzik, Jozef (author)
- Uppsala University,Uppsala universitet,Gastrointestinalkirurgi,Uppsala Univ, Sweden
-
- Sandström, Per (author)
- Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
-
- Björnsson, Bergthor (author)
- Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
-
- Hasselgren, Kristina (author)
- Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
-
show less...
-
(creator_code:org_t)
- 2023-02-23
- 2023
- English.
-
In: Cancers. - : MDPI AG. - 2072-6694. ; 15:5
- Related links:
-
https://doi.org/10.3...
-
show more...
-
https://umu.diva-por... (primary) (Raw object)
-
https://uu.diva-port... (primary) (Raw object)
-
https://liu.diva-por... (primary) (Raw object)
-
http://dx.doi.org/10... (free)
-
https://gup.ub.gu.se...
-
https://doi.org/10.3...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
https://lup.lub.lu.s...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Simple Summary Real-life data on the occurrence and treatment of synchronously detected liver and lung metastases from colorectal cancer are lacking. Through the merging of several Swedish nationwide patient quality registries, we aimed to answer these questions. We found that synchronous liver and lung colorectal metastases are rare and that a minority undergo resection of both metastatic sites, but if they do, they have an excellent survival. It is likely that a larger proportion of patients could be offered treatment that leads to a prolonged overall survival. We also found differences in regional treatment approaches across Sweden, but the reasons for this are unknown, which warrants further studies. Population-based data on the incidence and surgical treatment of patients with colorectal cancer (CRC) and synchronous liver and lung metastases are lacking as are real-life data on the frequency of metastasectomy for both sites and outcomes in this setting. This is a nationwide population-based study of all patients having liver and lung metastases diagnosed within 6 months of CRC between 2008 and 2016 in Sweden identified through the merging of data from the National Quality Registries on CRC, liver and thoracic surgery and the National Patient Registry. Among 60,734 patients diagnosed with CRC, 1923 (3.2%) had synchronous liver and lung metastases, of which 44 patients had complete metastasectomy. Surgery of liver and lung metastases yielded a 5-year OS of 74% (95% CI 57-85%) compared to 29% (95% CI 19-40%) if liver metastases were resected but not the lung metastases and 2.6% (95% CI 1.5-4%) if non-resected, p < 0.001. Complete resection rates ranged from 0.7% to 3.8% between the six healthcare regions of Sweden, p = 0.007. Synchronous liver and lung CRC metastases are rare, and a minority undergo the resection of both metastatic sites but with excellent survival. The reasons for differences in regional treatment approaches and the potential of increased resection rates should be studied further.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- liver metastases
- lung metastases
- colorectal cancer
- synchronous
- metastases
- incidence
- treatment
- colorectal cancer
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
Cancers
(Search for host publication in LIBRIS)
To the university's database