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Cardiac remodelling - Part 2: Clinical, imaging and laboratory findings. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology

Aimo, Alberto (author)
Scuola Super Sant Anna, Italy; Fdn Toscana Gabriele Monasterio, Italy,Univ Otago, New Zealand,Univ Med Ctr Groningen, Netherlands,Wroclaw Med Univ, Poland
Vergaro, Giuseppe (author)
Scuola Super Sant Anna, Italy; Fdn Toscana Gabriele Monasterio, Italy
Gonzalez, Arantxa (author)
Univ Navarra, Spain; Navarra Inst Hlth Res, Spain; Carlos III Inst Hlth, Spain
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Barison, Andrea (author)
Scuola Super Sant Anna, Italy; Fdn Toscana Gabriele Monasterio, Italy
Lupon, Josep (author)
Hosp Badalona Germans Trias & Pujol, Spain
Delgado, Victoria (author)
Hosp Badalona Germans Trias & Pujol, Spain
Richards, A. Mark (author)
Univ Otago, New Zealand
de Boer, Rudolf A. (author)
Univ Med Ctr Groningen, Netherlands
Thum, Thomas (author)
Med Univ Vienna, Austria; German Ctr Cardiovasc Res DZHK, Germany
Arfsten, Henrike (author)
Med Univ Vienna, Austria; German Ctr Cardiovasc Res DZHK, Germany
Hulsmann, Martin (author)
Med Univ Vienna, Austria
Falcao-Pires, Ines (author)
Univ Porto, Portugal
Diez, Javier (author)
Ctr Appl Med Res, Spain
Foo, Roger S. Y. (author)
Natl Univ Singapore Hosp, Singapore
Chan, Mark Yan Yee (author)
Natl Univ Singapore Hosp, Singapore
Anene-Nzelu, Chukwuemeka G. (author)
Natl Univ Singapore Hosp, Singapore
Abdelhamid, Magdy (author)
Cairo Univ, Egypt
Adamopoulos, Stamatis (author)
Onassis Cardiac Surg Ctr, Greece
Anker, Stefan D. (author)
Charite, Germany; Charite, Germany
Belenkov, Yuri (author)
Lomonosv Moscow State Univ, Russia
Gal, Tuvia B. (author)
Rabin Med Ctr, Israel
Cohen-Solal, Alain (author)
Hosp Lariboisiere, France
Bohm, Michael (author)
Univ Saarland, Germany
Chioncel, Ovidiu (author)
Univ Med & Pharm Carol Davila, Romania
Jankowska, Ewa A. (author)
Wroclaw Med Univ, Poland
Gustafsson, Finn (author)
Copenhagen Univ Hosp, Denmark
Hill, Loreena (author)
Karolinska Institutet,Queens Univ Belfast, North Ireland
Jaarsma, Tiny (author)
Linköpings universitet,Avdelningen för omvårdnad och reproduktiv hälsa,Medicinska fakulteten
Januzzi, James L. (author)
Massachusetts Gen Hosp, MA 02114 USA; Baim Inst Clin Res, MA USA
Jhund, Pardeep (author)
Univ Glasgow, Scotland
Lopatin, Yuri (author)
Volgograd State Med Univ, Russia
Lund, Lars H. (author)
Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
Metra, Marco (author)
Univ Brescia, Italy
Milicic, Davor (author)
Univ Zagreb, Croatia
Moura, Brenda (author)
Univ Porto, Portugal; Porto Armed Forces Hosp, Portugal
Mueller, Christian (author)
Univ Hosp, Switzerland
Mullens, Wilfried (author)
Hosp Oost Limburg, Belgium
Nunez, Julio (author)
Univ Valencia, Spain
Piepoli, Massimo F. (author)
Castelsangiovanni Hosp, Italy
Rakisheva, Amina (author)
Sci Res Inst Cardiol & Internal Med, Kazakhstan
Ristic, Arsen D. (author)
Univ Clin Ctr Serbia, Serbia; Univ Belgrade, Serbia
Rossignol, Patrick (author)
Univ Lorraine, France; CHRU Nancy, France
Savarese, Gianluigi (author)
Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
Tocchetti, Carlo G. (author)
Univ Naples Federico II, Italy
van Linthout, Sophie (author)
Charite Univ Med Berlin, Germany; German Ctr Cardiovasc Res DZHK, Germany
Volterrani, Maurizio (author)
IRCCS San Raffaele, Italy
Seferovic, Petar (author)
Univ Belgrade, Serbia; Serbian Acad Arts & Sci, Serbia
Rosano, Giuseppe (author)
Univ London, England
Coats, Andrew J. S. (author)
Univ Warwick, England
Emdin, Michele (author)
Scuola Super Sant Anna, Italy; Fdn Toscana Gabriele Monasterio, Italy
Bayes-Genis, Antoni (author)
Carlos III Inst Hlth, Spain; Hosp Badalona Germans Trias & Pujol, Spain; Univ Autonoma Barcelona, Spain
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 (creator_code:org_t)
2022-05-16
2022
English.
In: European Journal of Heart Failure. - : WILEY. - 1388-9842 .- 1879-0844. ; 24:6, s. 944-958
  • Research review (peer-reviewed)
Abstract Subject headings
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  • In patients with heart failure, the beneficial effects of drug and device therapies counteract to some extent ongoing cardiac damage. According to the net balance between these two factors, cardiac geometry and function may improve (reverse remodelling, RR) and even completely normalize (remission), or vice versa progressively deteriorate (adverse remodelling, AR). RR or remission predict a better prognosis, while AR has been associated with worsening clinical status and outcomes. The remodelling process ultimately involves all cardiac chambers, but has been traditionally evaluated in terms of left ventricular volumes and ejection fraction. This is the second part of a review paper by the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology dedicated to ventricular remodelling. This document examines the proposed criteria to diagnose RR and AR, their prevalence and prognostic value, and the variables predicting remodelling in patients managed according to current guidelines. Much attention will be devoted to RR in patients with heart failure with reduced ejection fraction because most studies on cardiac remodelling focused on this setting.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

Heart failure; Ejection fraction; Remodelling; Predictors; Imaging; Biomarkers; Therapies

Publication and Content Type

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