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Left-sided valvular heart disease and survival in out-of-hospital cardiac arrest: a nationwide registry-based study.

Dejby, Ellen (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden
Bhatt, Deepak L (författare)
Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Skoglund, Kristofer, 1976 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden; The Swedish Cardiopulmonary Resuscitation Registry, Centre of Registries, Västra Götaland, Gothenburg, Sweden
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Rawshani, Aidin, 1991 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden; The Swedish Cardiopulmonary Resuscitation Registry, Centre of Registries, Västra Götaland, Gothenburg, Sweden
Omerovic, Elmir, 1968 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden
Redfors, Björn (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden; Clinical Trial Center, Cardiovascular Research Foundation, New York, NY, USA; Department of Cardiology, New York-Presbyterian Hospital/Columbia University Medical Center, New York, USA
Myredal, Anna, 1975 (författare)
Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden
Petursson, Petur, 1973 (författare)
Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden
Angerås, Oskar, 1976 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden
Gustafsson, Arvid (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden
Isaksén, Daniella (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden
Herlitz, Johan, 1949 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden
Rawshani, Araz, 1986 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, University of Gothenburg, Institute of Medicine, Gothenburg, Sweden; Department of Cardiology, The Sahlgrenska University Hospital, Gothenburg, Sweden; The Swedish Cardiopulmonary Resuscitation Registry, Centre of Registries, Västra Götaland, Gothenburg, Sweden
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 (creator_code:org_t)
2023
2023
Engelska.
Ingår i: Scientific reports. - 2045-2322. ; 13:1
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Survival in left-sided valvular heart disease (VHD; aortic stenosis [AS], aortic regurgitation [AR], mitral stenosis [MS], mitral regurgitation [MR]) in out-of-hospital cardiac arrest (OHCA) is unknown. We studied all cases of OHCA in the Swedish Registry for Cardiopulmonary Resuscitation. All degrees of VHD, diagnosed prior to OHCA, were included. Association between VHD and survival was studied using logistic regression, gradient boosting and Cox regression. We studied time to cardiac arrest, comorbidities, survival, and cerebral performance category (CPC) score. We included 55,615 patients; 1948 with AS (3,5%), 384 AR (0,7%), 17 MS (0,03%), and 704 with MR (1,3%). Patients with MS were not described due to low case number. Time from VHD diagnosis to cardiac arrest was 3.7years in AS, 4.5years in AR and 4.1years in MR. ROSC occurred in 28% with AS, 33% with AR, 36% with MR and 35% without VHD. Survival at 30days was 5.2%, 10.4%, 9.2%, 11.4% in AS, AR, MR and without VHD, respectively. There were no survivors in people with AS presenting with asystole or PEA. CPC scores did not differ in those with VHD compared with no VHD. Odds ratio (OR) for MR and AR showed no difference in survival, while AS displayed OR 0.58 (95% CI 0.46-0.72), vs no VHD. AS is associated with halved survival in OHCA, while AR and MR do not affect survival. Survivors with AS have neurological outcomes comparable to patients without VHD.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

Humans
Out-of-Hospital Cardiac Arrest
Heart Valve Diseases
diagnosis
Mitral Valve Stenosis
Aortic Valve Stenosis
complications
Cardiopulmonary Resuscitation
Mitral Valve Insufficiency
complications
Aortic Valve Insufficiency
complications
Registries
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