id:"swepub:oai:gup.ub.gu.se/330197"
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- Enerbäck, HannaGothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology,Department of Orthodontics, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (author)
Effect of high-fluoride toothpaste and mouth rinse on the prevention of demineralized lesions during orthodontic treatment: a randomized controlled trial
- Article/chapterEnglish2023
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- Oxford University Press,2023
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- LIBRIS-ID:oai:gup.ub.gu.se/330197
- https://gup.ub.gu.se/publication/330197URI
- https://doi.org/10.1093/ejo/cjad044DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-215275URI
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- Language:English
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- Objective To evaluate the effect of high-fluoride mouth rinse and high-fluoride toothpaste on the development of demineralized lesions (DLs) during orthodontic treatment. Trial design Three-armed parallel-group randomized controlled trial. Methods The trial was performed with 270 adolescent orthodontic patients. Randomization was performed in blocks of 30, enrolling the patients into one of the following groups: the fluoride mouth rinse (FMR) group receiving 0.2% sodium fluoride (NaF) mouth rinse plus 1450 ppm fluoride (F) toothpaste; high-fluoride toothpaste (HFT) group receiving 5000 ppm F toothpaste; and the Control (CTR) group receiving 1450 ppm F toothpaste. Inclusion criteria were patients scheduled for treatment in both arches with fixed appliances and age between 12 and 20 years. The primary outcome variable was the proportion of participants with at least one new demineralized lesion as assessed on digital photos taken before and after treatment, analysed by a blinded clinician. The analysis included all teeth or teeth in the aesthetic zone, i.e. all central incisors, lateral incisors, and canines. A random sample of 30 participants was assessed to check intra- and inter-reliability. For pairwise comparison between groups, Fisher's non-parametric permutation test was used for continuous variables. Blinding was employed during the caries registration and data analysis. Recruitment October 2010 to December 2012 Results In total, 270 patients were randomized, of which 22 were excluded during treatment. Therefore, 248 participants were included in the study. The number of patients with an increase of & GE;1 DL, including only central- and lateral incisors and canines, during orthodontic treatment, was significantly lower in the HFT group, 51/85 60%, compared to the CTR group, 64/82 78%, RR 0.77 (CI 0.62; 0.95), P = .01 and in the FMR group, 47/81 58%, compared to the CTR group, RR 0.74 (CI 0.60; 0.92), P < .01. Conclusions To prevent demineralized lesions in the aesthetic zone, high-fluoride mouth rinse and high-fluoride toothpaste may be recommended. Limitations The protocol was not registered, and the present study did not use a double-blinded design.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Odontologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Dentistry hsv//eng
- fluoride
- mouth rinse
- high-fluoride toothpaste
- white spot lesion
- demineralization
- fixed appliance
- orthodontics
- fixed brace treatment
- multi bracket appliance treatment
- demineralization
Added entries (persons, corporate bodies, meetings, titles ...)
- Lovgren, M. L.Department of Orthodontics, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (author)
- Strömberg, NicklasUmeå universitet,Institutionen för odontologi(Swepub:umu)nist0001 (author)
- Westerlund, Anna,1970Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology,Department of Orthodontics, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Public Dental Service, Mölndal, Sweden(Swepub:gu)xgoraa (author)
- Göteborgs universitetInstitutionen för odontologi (creator_code:org_t)
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- In:European Journal of Orthodontics: Oxford University Press45:5, s. 477-4840141-53871460-2210
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