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One-year survival a...
One-year survival and outcomes of infants born at 22 and 23 weeks of gestation in Sweden 2004-2007, 2014-2016 and 2017-2019
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- Farooqi, Aijaz (författare)
- Umeå University,Umeå universitet,Pediatrik,Umea Univ, Sweden
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- Håkansson, Stellan (författare)
- Umeå University,Umeå universitet,Pediatrik,Pediatrics, Swedish Neonatal Quality Register, Umeå Universitet, Umeå, Sweden,Umea Univ, Sweden; Umea Univ, Sweden
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- Serenius, Fredrik (författare)
- Uppsala University
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- Kallen, Karin (författare)
- Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Miljöepidemiologi,Forskargrupper vid Lunds universitet,Tornbladinstitutet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Environmental Epidemiology,Lund University Research Groups,Tornblad Institute
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- Björklund, Lars (författare)
- Departments of Clinical Sciences and Pediatrics, Skåne University Hospital Lund, Lund, Sweden,Skane Univ Hosp Lund, Sweden; Skane Univ Hosp Lund, Sweden
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- Normann, E. (författare)
- Uppsala University
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- Domellöf, Magnus, 1963- (författare)
- Umeå University,Umeå universitet,Pediatrik,Umea Univ, Sweden
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- Ådén, Ulrika (författare)
- Karolinska Institute,Karolinska Institutet
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- Abrahamsson, Thomas (författare)
- Linköping University,Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus
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- Elfvin, Anders, 1971 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Department of Pediatrics, Institute of Clinical Sciences, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden; Department of Pediatrics, Sahlgrenska University Hospital, Göteborg, Sweden,Univ Gothenburg, Sweden; Sahlgrens Univ Hosp, Sweden
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- Savman, K. (författare)
- Department of Pediatrics, Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrens Univ Hosp, Sweden
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- Bergstrom, P. U. (författare)
- Karolinska Institute,Karolinska Institutet
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- Stephansson, O. (författare)
- Karolinska Institute,Karolinska Institutet
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- Ley, David (författare)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neonatalogi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Neonatology,Lund University Research Groups
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- Hellstrom-Westas, Lena (författare)
- Uppsala University
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- Norman, M. (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska University Hospital
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(creator_code:org_t)
- BMJ Publishing Group Ltd, 2024
- 2024
- Engelska.
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Ingår i: Archives of Disease in Childhood-Fetal and Neonatal Edition. - : BMJ Publishing Group Ltd. - 1359-2998 .- 1468-2052. ; 109:1, s. 10-17
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- ObjectiveTo explore associations between perinatal activity and survival in infants born at 22 and 23 weeks of gestation in Sweden. Design/SettingData on all births at 22 and 23 weeks' gestational age (GA) were prospectively collected in 2004-2007 (T1) or obtained from national registers in 2014-2016 (T2) and 2017-2019 (T3). Infants were assigned perinatal activity scores based on 3 key obstetric and 4 neonatal interventions. Main outcomeOne-year survival and survival without major neonatal morbidities (MNM): intraventricular haemorrhage grade 3-4, cystic periventricular leucomalacia, surgical necrotising enterocolitis, retinopathy of prematurity stage 3-5 or severe bronchopulmonary dysplasia. The association of GA-specific perinatal activity score and 1-year survival was also determined. Results977 infants (567 live births and 410 stillbirths) were included: 323 born in T1, 347 in T2 and 307 in T3. Among live-born infants, survival at 22 weeks was 5/49 (10%) in T1 and rose significantly to 29/74 (39%) in T2 and 31/80 (39%) in T3. Survival was not significantly different between epochs at 23 weeks (53%, 61% and 67%). Among survivors, the proportions without MNM in T1, T2 and T3 were 20%, 17% and 19% for 22 weeks and 17%, 25% and 25% for 23 weeks' infants (p>0.05 for all comparisons). Each 5-point increment in GA-specific perinatal activity score increased the odds for survival in first 12 hours of life (adjusted OR (aOR) 1.4; 95% CI 1.3 to 1.6) in addition to 1-year survival (aOR 1.2; 95% CI 1.1 to 1.3), and among live-born infants it was associated with increased survival without MNM (aOR 1.3; 95% CI 1.1 to 1.4). ConclusionIncreased perinatal activity was associated with reduced mortality and increased chances of survival without MNM in infants born at 22 and 23 weeks of GA.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- neonatology
- paediatrics
- extremely preterm infants
- perinatal management
- birth
- mortality
- care
- association
- Pediatrics
- neonatology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Farooqi, Aijaz
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Håkansson, Stell ...
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Serenius, Fredri ...
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Kallen, Karin
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Björklund, Lars
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Normann, E.
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Domellöf, Magnus ...
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Ådén, Ulrika
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Abrahamsson, Tho ...
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Elfvin, Anders, ...
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Savman, K.
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Bergstrom, P. U.
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Stephansson, O.
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Ley, David
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Hellstrom-Westas ...
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Norman, M.
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Pediatrik
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Göteborgs universitet
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Umeå universitet
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Linköpings universitet
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