Surgical management of acute appendicitis during the European COVID-19 second wave: safe and effective

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Surgical management of acute appendicitis during the European COVID-19 second wave: safe and effective

Forssten, Maximilian Peter, 1996- (author): Örebro universitet,Institutionen för medicinska vetenskaper,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro University, Örebro, Sweden

Kaplan, Lewis J. (author): Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA; Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, USA

Tolonen, Matti (author): Helsinki University Hospital HUS Meilahden Tornisairaala, Helsinki, Finland

Martinez-Casas, Isidro (author): Servicio de Cirugía General, Unidad de Cirugía de Urgencias, Hospital Universitario Virgen del Rocío, Seville, Spain

Cao, Yang, Associate Professor, 1972- (author): Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics

Walsh, Thomas N. (author): Royal College of Surgeons in Ireland Medical University, Busaiteen, Bahrain

Bass, Gary Alan, 1979- (author): Örebro universitet,Institutionen för medicinska vetenskaper,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro, Sweden; Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA; Center for Perioperative Outcomes Research and Transformation (CPORT), University of Pennsylvania, Philadelphia, USA; Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania, Philadelphia, USA

Mohseni, Shahin, 1978- (author): Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Division of Trauma and Emergency Surgery, Örebro University Hospital, Örebro, Sweden

Ahl Hulme, Rebecka (author)

Biloslavo, Alan (author)

Kurihara, Hayato (author)

Pereira, Jorge (author)

Pourlotfi, Arvid (author)

Ryan, Éanna J. (author)

Louri, Nayef (author)

Nedham, Fatema (author)

Walsh, Thomas Noel (author)

Hashem, Jamal (author)

Corbally, Martin (author)

Farhan, Abeer (author)

Al Hamad, Hamad (author)

Elhennawy, Rawan (author)

AlKooheji, Mariam (author)

AlYusuf, Manar (author)

Aknouche, Wissal (author)

Zeidan, Anas A. (author)

Alsaffar, Yusuf S. (author)

Lipping, Edgar (author)

Talving, Peep (author)

Saar, Sten (author)

Graumann, Katrina (author)

Kibuspuu, Liis (author)

Harkov, Eduard (author)

Aaltonen, Gisele (author)

Sillman, Iines S. (author)

Haapanen, Sami (author)

Lampela, Hanna (author)

Sammalkorpi, Henna (author)

Eskola, Sofia (author)

Laakso, Altti (author)

Back, Johan (author)

Kettunen, Ulla (author)

Nummi, Antti M. (author)

Szwedyc, Anika (author)

Nykänen, Taina (author)

Rantala, Rolle (author)

Mäkäräinen-Uhlbäck, Elisa J. (author)

Meriläinen, Sanna A. (author)

Huhta, Heikki I. (author)

Rintala, Jukka M.J. (author)

Laitakari, Kirsi E.M. (author)

Lietzen, Elina (author)

Salminen, Paulina (author)

Rapola, Risto K.A. (author)

Zangouri, Vahid (author)

Karami, Mohammad Y. (author)

Tahmasebi, Sedigheh (author)

Akrami, Majid (author)

Golchini, Alireza (author)

Bahrami, Faranak (author)

Johnston, Sean M. (author)

Lim, Sean T. (author)

Ahonkhai, Irele Ifijeh (author)

Eltagani, Eltahir (author)

Ryan, Odhran K. (author)

O’Driscoll-Collins, Ailbhe (author)

O’Neill, Aine (author)

Penny, Zakiya (author)

Kelly, Orlaith (author)

Cullinane, Carolyn (author)

Reynolds, Ian (author)

Heneghan, Helen (author)

Martin, Sean (author)

Winter, Des (author)

Davey, Matthew (author)

Alkhattab, Maha (author)

Lowery, Aoife J. (author)

Kerin, Michael J. (author)

Hogan, Aisling M. (author)

Davey, Martin S. (author)

Oh, Ke En (author)

Kabir, Syed Mohammad Umar (author)

Huan, Huilun (author)

Aziz, Charlotte (author)

Sugrue, Michael (author)

Ryan, Jessica M. (author)

Connelly, Tara M. (author)

Alhazmi, Mohammad (author)

Al-Mukhaizeem, Youssef (author)

Cooke, Fiachra (author)

Neary, Peter M. (author)

Hill, Arnold D.K. (author)

Boland, Michael R. (author)

Lloyd, Angus J. (author)

Fallon, Frances (author)

Cleere, Eoin F. (author)

Toale, James (author)

Boland, Patrick A. (author)

Devine, Michael (author)

Keady, Conor (author)

Caragounis, Eva Corina (author): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery

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(creator_code:org_t)

2023-01-19
2023
English.
In: European Journal of Trauma and Emergency Surgery. - : Springer Science and Business Media LLC. - 1863-9933 .- 1615-3146 .- 1863-9941. ; 49, s. 57-67

Related links:: https://doi.org/10.1...; show more...; https://gup.ub.gu.se...; https://doi.org/10.1...; https://urn.kb.se/re...; http://kipublication...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Introduction: The COVID-19 (SARS-CoV-2) pandemic drove acute care surgeons to pivot from long established practice patterns. Early safety concerns regarding increased postoperative complication risk in those with active COVID infection promoted antibiotic-driven non-operative therapy for select conditions ahead of an evidence-base. Our study assesses whether active or recent SARS-CoV-2 positivity increases hospital length of stay (LOS) or postoperative complications following appendectomy. Methods: Data were derived from the prospective multi-institutional observational SnapAppy cohort study. This preplanned data analysis assessed consecutive patients aged ≥ 15years who underwent appendectomy for appendicitis (November 2020–May 2021). Patients were categorized based on SARS-CoV-2 seropositivity: no infection, active infection, and prior infection. Appendectomy method, LOS, and complications were abstracted. The association between SARS-CoV-2 seropositivity and complications was determined using Poisson regression, while the association with LOS was calculated using a quantile regression model. Results: Appendectomy for acute appendicitis was performed in 4047 patients during the second and third European COVID waves. The majority were SARS-CoV-2 uninfected (3861, 95.4%), while 70 (1.7%) were acutely SARS-CoV-2 positive, and 116 (2.8%) reported prior SARS-CoV-2 infection. After confounder adjustment, there was no statistically significant association between SARS-CoV-2 seropositivity and LOS, any complication, or severe complications. Conclusion: During sequential SARS-CoV-2 infection waves, neither active nor prior SARS-CoV-2 infection was associated with prolonged hospital LOS or postoperative complication. Despite early concerns regarding postoperative safety and outcome during active SARS-CoV-2 infection, no such association was noted for those with appendicitis who underwent operative management.

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By the author/editor: Forssten, Maximi ...; Kaplan, Lewis J.; Tolonen, Matti; Martinez-Casas, ...; Cao, Yang, Assoc ...; Walsh, Thomas N.; show more...; Bass, Gary Alan, ...; Mohseni, Shahin, ...; Ahl Hulme, Rebec ...; Biloslavo, Alan; Kurihara, Hayato; Pereira, Jorge; Pourlotfi, Arvid; Ryan, Éanna J.; Louri, Nayef; Nedham, Fatema; Walsh, Thomas No ...; Hashem, Jamal; Corbally, Martin; Farhan, Abeer; Al Hamad, Hamad; Elhennawy, Rawan; AlKooheji, Maria ...; AlYusuf, Manar; Aknouche, Wissal; Zeidan, Anas A.; Alsaffar, Yusuf ...; Lipping, Edgar; Talving, Peep; Saar, Sten; Graumann, Katrin ...; Kibuspuu, Liis; Harkov, Eduard; Aaltonen, Gisele; Sillman, Iines S ...; Haapanen, Sami; Lampela, Hanna; Sammalkorpi, Hen ...; Eskola, Sofia; Laakso, Altti; Back, Johan; Kettunen, Ulla; Nummi, Antti M.; Szwedyc, Anika; Nykänen, Taina; Rantala, Rolle; Mäkäräinen-Uhlbä ...; Meriläinen, Sann ...; Huhta, Heikki I.; Rintala, Jukka M ...; Laitakari, Kirsi ...; Lietzen, Elina; Salminen, Paulin ...; Rapola, Risto K. ...; Zangouri, Vahid; Karami, Mohammad ...; Tahmasebi, Sedig ...; Akrami, Majid; Golchini, Alirez ...; Bahrami, Faranak; Johnston, Sean M ...; Lim, Sean T.; Ahonkhai, Irele ...; Eltagani, Eltahi ...; Ryan, Odhran K.; O’Driscoll-Colli ...; O’Neill, Aine; Penny, Zakiya; Kelly, Orlaith; Cullinane, Carol ...; Reynolds, Ian; Heneghan, Helen; Martin, Sean; Winter, Des; Davey, Matthew; Alkhattab, Maha; Lowery, Aoife J.; Kerin, Michael J ...; Hogan, Aisling M ...; Davey, Martin S.; Oh, Ke En; Kabir, Syed Moha ...; Huan, Huilun; Aziz, Charlotte; Sugrue, Michael; Ryan, Jessica M.; Connelly, Tara M ...; Alhazmi, Mohamma ...; Al-Mukhaizeem, Y ...; Cooke, Fiachra; Neary, Peter M.; Hill, Arnold D.K ...; Boland, Michael ...; Lloyd, Angus J.; Fallon, Frances; Cleere, Eoin F.; Toale, James; Boland, Patrick ...; Devine, Michael; Keady, Conor; Caragounis, Eva ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Surgery

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Infectious Medic ...

Articles in the publication: European Journal ...

By the university: University of Gothenburg; Örebro University; Karolinska Institutet

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Surgical management of acute appendicitis during the European COVID-19 second wave: safe and effective

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