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Isolated hypertherm...
Isolated hyperthermic perfusions for cutaneous melanoma in-transit metastasis of the limb and uveal melanoma metastasis to the liver
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- Huibers, Anne, 1986 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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Depalo, D. K. (author)
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Perez, M. C. (author)
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Zager, J. S. (author)
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- Olofsson Bagge, Roger, 1978 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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(creator_code:org_t)
- 2023
- 2023
- English.
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In: Clinical & Experimental Metastasis. - 0262-0898.
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- Patients with cutaneous melanoma can develop in-transit metastases (ITM), most often localized to limbs. For patients with uveal melanoma that develop metastatic disease, the overall majority develop isolated liver metastases. For these types of metastases, regional cancer therapies have evolved as effective treatments. Isolated limb perfusion (ILP), isolated limb infusion (ILI), isolated hepatic perfusion (IHP) and percutaneous hepatic perfusion (PHP) achieve a high local concentration of chemotherapy with minimal systemic exposure. This review discusses the mechanism and available literature on locoregional treatment modalities in the era of modern immunotherapy.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- In transit metastasis
- Uveal melanoma
- Isolated limb perfusion
- Isolated
- limb infusion
- Isolated hepatic perfusion
- Percutaneous hepatic
- perfusion
- term-follow-up
- malignant-melanoma
- ocular melanoma
- choroidal melanoma
- infusion
- chemotherapy
- progression
- melphalan
- cancer
- prognosis
- Oncology
Publication and Content Type
- ref (subject category)
- for (subject category)
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