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  • Hellström, SaraDepartment of Obstetrics and Gynecology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Division of Neonatology, Department of Pediatrics, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Obstet & Gynecol, Reg Vastra Gotaland, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Queen Silv Childrens Hosp, Div Neonatol, Dept Pediat, Gothenburg, Sweden. (författare)

A follow up on the feasibility after national implementation of magnesium sulfate for neuroprotection prior to preterm birth.

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • John Wiley & Sons,2023

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/332403
  • https://gup.ub.gu.se/publication/332403URI
  • https://doi.org/10.1111/aogs.14673DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-214393URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-198681URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-523245URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:153918027URI
  • https://lup.lub.lu.se/record/f1cd4fef-1dc3-4973-abc0-979db648b81cURI

Kompletterande språkuppgifter

  • Språk:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies|Frimurarfonden Barnhusdirektionen Foundation [GLS 7000991]; Linnea and Josef Carlsson Foundaton; Rune and Ulla Almloevs stiftelse SEB; Stiftelsen Mary von Sydows, foedd Wijk, donationsfond; Stiftelserna Wilhelm och Martina Lundgrens [GLS-964281]; ALF Agreement [2019- 2941, ALFGBG-77860, ALFGBG-75710]; Vetenskapsradet [ALFGBG-718591]; Swedish government; county councils; [2019-01320]
  • The risk for brain injury manifested as cerebral palsy is higher in very preterm born children than in term. Prenatal administration of magnesium sulfate (MgSO4 ) has been shown to be neuroprotective and reduces the proportion of very preterm born children later diagnosed with cerebral palsy. A Swedish national clinical practice guideline was implemented in March 2020, stipulating the administration of a single intravenous dose of 6g MgSO4 1-24h prior to delivery before gestational age 32+0, aiming for 90% treatment coverage. The aim of this study was to evaluate the feasibility of this new clinical practice guideline in the first year of its implementation.Data on MgSO4 treatment were collected by reviewing the medical charts of women who gave birth to live born children in gestational age 22+0-31+6 during the period of March 1, 2020 to February 28, 2021, at five Swedish university hospitals. Women with pre-eclampsia, eclampsia, or high elevated liver enzymes low platelets (HELLP) were excluded.A total of 388 women were eligible and 79% received treatment with MgSO4 . Of the 21% not receiving treatment, 9% did not receive treatment due to lack of knowledge about the clinical practice guideline, 9% were not possible to treat and 3% had missing data. The proportion treated increased from 72% to 87% from the first to the last 3months. Of those treated, 81% received the drug within the stipulated timeframe (mean 8.7h, median 3.4h).There was a positive trend over time in the proportion of women receiving MgSO4 treatment, but the a priori target of 90% was not reached during the first year of implementation. Our findings indicate that this target could be reached with additional information to clinicians.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Jonsdotter, AndreaDepartment of Obstetrics and Gynecology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Obstet & Gynecol, Reg Vastra Gotaland, Gothenburg, Sweden.;Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Ctr Perinatal Med & Hlth, Gothenburg, Sweden. (författare)
  • Jonsson, Maria,1966-Uppsala University,Uppsala universitet,Klinisk obstetrik(Swepub:uu)marjo155 (författare)
  • Pettersson, KarinKarolinska Institute,Karolinska Institutet (författare)
  • Saltvedt, SisselDepartment of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden,Karolinska Inst, Karolinska Univ Hosp, Dept Womens & Childrens Hlth, Stockholm, Sweden. (författare)
  • Herbst, AndreasLund University,Lunds universitet,Valid intrapartal övervakning och intervention för perinatal säkerhet,Forskargrupper vid Lunds universitet,Valid IntraPartum Surveillance and Interventions to make Pregnancy Safe,Lund University Research Groups,Skåne University Hospital(Swepub:lu)gyn-ahe (författare)
  • Ågren, Johan,1966-Uppsala University,Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning(Swepub:uu)johaagre (författare)
  • Ådén, Ulrika,1972-Linköping University,Karolinska Institutet,Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus,Karolinska Inst, Karolinska Univ Hosp, Dept Womens & Childrens Hlth, Stockholm, Sweden.;Linköping Univ, Dept Biomed & Clin Sci, Linköping, Sweden.,Karolinska University Hospital(Swepub:lu)ul8653ad (författare)
  • Domellöf, Magnus,1963-Umeå University,Umeå universitet,Pediatrik,Umeå Univ, Dept Clin Sci Pediat, Umeå, Sweden.(Swepub:umu)mado0002 (författare)
  • Hagberg, HenrikDepartment of Obstetrics and Gynecology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Obstet & Gynecol, Reg Vastra Gotaland, Gothenburg, Sweden.;Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Ctr Perinatal Med & Hlth, Gothenburg, Sweden. (författare)
  • Carlsson, Ylva,1975Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology,Department of Obstetrics and Gynecology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Obstet & Gynecol, Reg Vastra Gotaland, Gothenburg, Sweden.;Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Ctr Perinatal Med & Hlth, Gothenburg, Sweden.(Swepub:gu)xcarly (författare)
  • Department of Obstetrics and Gynecology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Division of Neonatology, Department of Pediatrics, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, SwedenSahlgrens Univ Hosp, Dept Obstet & Gynecol, Reg Vastra Gotaland, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Queen Silv Childrens Hosp, Div Neonatol, Dept Pediat, Gothenburg, Sweden. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta obstetricia et gynecologica Scandinavica: John Wiley & Sons102:12, s. 1741-17481600-04120001-6349

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