Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the 'Life's Essential 8' (LE8) concept of the American Heart Association (AHA).Design: Population-based cohort study.Setting: Swedish CardioPulmonary bioImage Study (SCAPIS).Population: A total of 8871 women from SCAPIS were included.Methods: Information on cardiovascular health in middle age was collected from SCAPIS and linked to pregnancy weight data obtained from the Swedish Medical Birth Register, with an average follow-up time of 24.5 years. An LE8 score between 0 and 100 was determined, where a score under 60 points was defined as poor cardiovascular health. Binary logistic regression and restricted cubic splines were used.Main outcome measures: Cardiovascular health according to LE8 in middle age.Results: The odds of having poor cardiovascular health in middle age were significantly higher in women who had overweight (adjusted odds ratio, aOR 3.30, 95% CI 2.82-3.88) or obesity (aOR 7.63, 95% CI 5.86-9.94), compared with women classified as being of normal weight in pregnancy. Higher odds were also found for excessive GWG (aOR 1.31, 95% CI 1.09-1.57), compared with women who gained weight within the recommendations. Conclusions: A high BMI in early pregnancy and excessive GWG were associated with greater odds of poor cardiovascular health in middle age. Although further studies are needed, our results highlight pregnancy as an important period to support long-term cardiovascular health.
Herraiz-Adillo, ÁngelLinköping University,Linköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten(Swepub:liu)anghe58
(författare)
Ahlqvist, Viktor H.Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden
(författare)
Higueras-Fresnillo, SaraLinköping University,Linköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten,Univ Autonoma Madrid, Spain,Autonomous University of Madrid(Swepub:liu)sarhi56
(författare)
Berglind, DanielKarolinska Institute,Stockholm School of Economics,Handelshögskolan i Stockholm,Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Centre for Epidemiology and Community Medicine, Region Stockholm, Stockholm, Sweden; Center for Wellbeing, Welfare and Happiness, Stockholm School of Economics, Stockholm, Sweden,Karolinska Inst, Sweden; Ctr Epidemiol & Community Med, Sweden; Ctr Wellbeing Welf & Happiness, Sweden,Stockholm Regional Council
(författare)
Daka, Bledar,1976Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,University of Gothenburg,School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sweden(Swepub:gu)xdakbl
(författare)
Lenander, CeciliaLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups(Swepub:lu)med-cl2
(författare)
Sundstrom, JohanUppsala University,University of New South Wales
(författare)
Östgren, Carl JohanLinköping University,Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Vårdcentralen Ekholmen(Swepub:liu)caros18
(författare)
Rådholm, KarinLinköping University,Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Vårdcentralen Kärna,Univ New South Wales, Australia,University of New South Wales(Swepub:liu)karra46
(författare)
Henriksson, PontusLinköping University,Linköpings universitet,Avdelningen för samhälle och hälsa,Medicinska fakulteten(Swepub:liu)ponhe11
(författare)
Linköpings universitetInstitutionen för hälsa, medicin och vård
(creator_code:org_t)
Sammanhörande titlar
Ingår i:BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY: John Wiley & Sons1470-03281471-0528