id:"swepub:oai:gup.ub.gu.se/335462"
Search: id:"swepub:oai:gup.ub.gu.se/335462" > Key learning on the...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Padhani, Anwar R. (author)
Key learning on the promise and limitations of MRI in prostate cancer screening
- Article/chapterEnglish2024
Publisher, publication year, extent ...
- 2024
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/335462
- https://gup.ub.gu.se/publication/335462URI
- https://doi.org/10.1007/s00330-024-10626-6DOI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- MRI retains its ability to reduce the harm of prostate biopsies by decreasing biopsy rates and the detection of indolent cancers in population-based screening studies aiming to find clinically significant prostate cancers. Limitations of low positive predictive values and high reader variability in diagnostic performance require optimisations in patient selection, imaging protocols, interpretation standards, diagnostic thresholds, and biopsy methods. Improvements in diagnostic accuracy could come about through emerging technologies like risk calculators and polygenic risk scores to select men for MRI. Furthermore, artificial intelligence and workflow optimisations focused on streamlining the diagnostic pathway, quality control, and assurance measures will improve MRI variability. Clinical relevance statement MRI significantly reduces harm in prostate cancer screening, lowering unnecessary biopsies and minimizing the overdiagnosis of indolent cancers. MRI maintains the effective detection of high-grade cancers, thus improving the overall benefit-to-harm ratio in population-based screenings with or without using serum prostate-specific antigen (PSA) for patient selection. Key Points center dot The use of MRI enables the harm reduction benefits seen in individual early cancer detection to be extended to both risk-stratified and non-stratified prostate cancer screening populations. center dot MRI limitations include a low positive predictive value and imperfect reader variability, which require standardising interpretations, biopsy methods, and integration into a quality diagnostic pathway. center dot Current evidence is based on one-time point use of MRI in screening; MRI effectiveness in multiple rounds of screening is not well-documented.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
- Prostatic neoplasms
- Diagnosis
- Multiparametric magnetic resonance imaging
- Image-Guided Biopsy (Screening)
Added entries (persons, corporate bodies, meetings, titles ...)
- Godtman, Rebecka Arnsrud,1981Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology(Swepub:gu)xgodre (author)
- Schoots, Ivo G. (author)
- Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för urologi (creator_code:org_t)
Related titles
- In:EUROPEAN RADIOLOGY0938-79941432-1084
Internet link
Find in a library
- EUROPEAN RADIOLOGY (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Padhani, Anwar R ...
- Godtman, Rebecka ...
- Schoots, Ivo G.
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Radiology Nuclea ...
- Articles in the publication
- EUROPEAN RADIOLO ...
- By the university
- University of Gothenburg
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
