Uterus transplantation as an infertility treatment

• Uterus transplantation (UTx) has during the past two decades evolved as the first treatment for absolute uterine factor infertility (AUFI). Our team started a step-by-step animal research project to understand if UTx was a feasible option and to optimize the procedure before possible introduction in the human. Research was initiated in rodents and was then further developed in animal models of larger domestic species and primates. In 2012, our team in Sweden launched the first clinical UTx trial and with the announcement of the world's first live birth after UTx in 2014. After that, several UTx trials were started and with results gradually evolving. In the present chapter, we will outline possible patient groups for UTx, surgery of UTx, clinical outcomes of trials and assisted reproduction in UTx patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Nyckelord

Animal models

Human

Infertility

Surgery

Transplantation

Uterus

Publikations- och innehållstyp

ref (ämneskategori)

kap (ämneskategori)