Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005

• Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl aminolevulinate for the treatment (and prevention) of nonmelanoma skin cancers. A systematic literature review was conducted (using MEDLINE), and recommendations were made on the basis of the quality of evidence for efficacy, safety/tolerability, cosmetic outcome, and patient satisfaction/preference. Topical PDT is highly effective in the treatment of actinic keratoses, Bowen's disease, superficial and thin nodular basal cell carcinomas, with cosmesis typically superior to that achieved with existing standard therapies. PDT may also be a means of preventing certain nonmelanoma skin cancers in immunosuppressed patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)

Nyckelord

Aminolevulinic Acid/analogs & derivatives/therapeutic use

Australia/epidemiology

Basal Cell Nevus Syndrome/drug therapy

Bowen's Disease/drug therapy

Carcinoma

Basal Cell/drug therapy/pathology

Carcinoma

Squamous Cell/drug therapy

Double-Blind Method

Humans

Immunocompromised Host

Incidence

Keratosis/drug therapy

Multicenter Studies

Patient Satisfaction

*Photochemotherapy/methods/standards

Photosensitivity Disorders/drug therapy

Randomized Controlled Trials

Skin Diseases/drug therapy

Skin Neoplasms/*drug therapy/epidemiology/prevention & control

United States/epidemiology

Publikations- och innehållstyp

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