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Functional long-ter...
Functional long-term outcome of a free jejunal transplant reconstruction following chemoradiotherapy and radical resection for hypopharyngeal and proximal oesophageal carcinoma
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- Bergquist, Henrik, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
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- Ejnell, Hasse, 1948 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
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- Fogdestam, Ingemar, 1941 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för plastikkirurgi,Institute of Surgical Sciences, Department of Plastic Surgery
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- Mark, Hans, 1961 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för plastikkirurgi,Institute of Surgical Sciences, Department of Plastic Surgery
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- Mercke, Claes, 1941 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för onkologi,Institute of Selected Clinical Sciences, Department of Oncology
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- Lundell, Lars, 1946 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för kirurgi,Institute of Surgical Sciences, Department of Surgery
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- Ruth, Magnus, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
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(creator_code:org_t)
- 2004
- 2004
- English.
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In: Digestive surgery. ; :21, s. 426-433
- Related links:
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https://gup.ub.gu.se...
Abstract
Subject headings
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- BACKGROUND/AIMS: To evaluate the functional outcome of a reconstruction by a free vascularized jejunal transplant combined with a voice prosthesis after chemoradiotherapy and surgery for proximal oesophageal or hypopharyngeal cancer. METHODS: Seven patients (6 men, mean age 52 years, range 28-70) with squamous cell cancer in the proximal oesophagus (n = 6) or the hypopharynx received preoperative chemoradiotherapy (40.8 Gy, cisplatinum and 5-FU) followed by a circumferential pharyngolaryngectomy and resection of the proximal oesophagus. A single-stage reconstruction was carried out with a free jejunal transplant using a microsurgical technique. A tracheojejunal puncture and insertion of a voice prosthesis (Provox I) was performed after 3 months in suitable cases. RESULTS: All operations had a per- and postoperative uneventful course. Five patients were alive after a mean follow-up time of 5 years and 7 months after surgery (range 3 years 4 months to 7 years 10 months), while 2 patients died from metastases within 2 years after surgery. Postoperative examination showed histopathological down-staging in all cases. Relief of dysphagia was achieved in most cases. Good or average speech was recorded in 3 patients. CONCLUSION: Reconstruction after radical resection for proximal oesophageal and hypopharyngeal cancer can be carried out with low mortality, acceptable morbidity and a promising functional outcome.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)
Keyword
- Oesophageal cancer
- free jejunal reconstruction
- microvascular surgery
- voice prosthesis
- quality of life
Publication and Content Type
- ref (subject category)
- art (subject category)
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Bergquist, Henri ...
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Ejnell, Hasse, 1 ...
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Fogdestam, Ingem ...
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Mark, Hans, 1961
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Mercke, Claes, 1 ...
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Lundell, Lars, 1 ...
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Ruth, Magnus, 19 ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Otorhinolaryngol ...
- Articles in the publication
- Digestive surger ...
- By the university
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University of Gothenburg