Use of 2-tracer PET to diagnose gastrointestinal stromal tumour and pheochromocytoma in patients with Carney triad and neurofibromatosis type 1

• There is rapid evolution in the functional imaging of tumours. In two patients with concomitant pheochromocytoma and gastrointestinal stromal tumour (GIST), previously unrecognized tumours were visualized by combined 2-tracer positron emission tomography (PET), which also provided precise information about tumour type. PET imaging led to radical resection and the diagnoses were histopathologically confirmed. GISTs from the Carney patient and the patient with neurofibromatosis type 1 (NF1) both lacked KIT mutations.

Keyword

Adrenal Gland Neoplasms/*radionuclide imaging

Female

Fluorodeoxyglucose F18/diagnostic use

Gastrointestinal Stromal Tumors/*radionuclide imaging

Humans

Leiomyoma/*complications

Male

Mediastinal Neoplasms/*complications

Middle Aged

Neurofibromatosis 1/*complications/radionuclide imaging

Paraganglioma

Extra-Adrenal/*complications

Pheochromocytoma/*radionuclide imaging

Positron-Emission Tomography/*methods

Radiopharmaceuticals/diagnostic use

Publication and Content Type

ref (subject category)

art (subject category)