Randomized trial of health-related quality of life after open and laparoscopic surgery for colon cancer

• BACKGROUND: Randomized controlled trials (RCTs) have reported improved or unchanged three-year survival following laparoscopic colon resection (LCR) for colon cancer compared with that following open resection (OCR). The aim of this study was to determine health-related quality of life (HRQL) in patients randomized to laparoscopic or open resection for colon cancer. METHODS: In total, 285 patients (130 LCR, 155 OCR) from seven Swedish centers were included. HRQL was assessed preoperatively and at 2, 4, and 12 weeks postoperatively with the EQ-5D and EORTC QLQ-C30 instruments. RESULTS: The LCR patients did significantly better on the social function component of the EORTC QLQ-C30 at two and four weeks and on the role function component at two weeks. CONCLUSION: Laparoscopic resection for colon cancer improved quality of life during the first postoperative month.

Nyckelord

Aged

*Colectomy

Colonic Neoplasms/psychology/*surgery

Female

*Health Status

Humans

Interpersonal Relations

*Laparoscopy

Male

Postoperative Period

*Quality of Life

Questionnaires

Role

Time Factors

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)