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Can brain natriuret...
Can brain natriuretic peptide (BNP) be used as a screening tool in general practice?
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- Schaufelberger, Maria, 1954 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Bergh, Claes-Håkan, 1951 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Caidahl, Kenneth, 1949 (author)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin,Institute of Internal Medicine
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- Eggertsen, Robert, 1948 (author)
- Gothenburg University,Göteborgs universitet,Extern,Institutionen för samhällsmedicin, Avdelningen för allmänmedicin,External,Institute of Community Medicine, Dept of Primary Health Care
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Furenäs, Eva (author)
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- Lindstedt, Göran, 1937 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine
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Nilsson, Thomas (author)
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Stefferud, Kari (author)
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- Swedberg, Karl, 1944 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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(creator_code:org_t)
- 2009-07-12
- 2004
- English.
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In: Scandinavian journal of primary health care. - : Informa UK Limited. - 0281-3432 .- 1502-7724. ; 22:3, s. 187-90
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Abstract
Subject headings
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- OBJECTIVE:To investigate plasma brain natriuretic peptide (p-BNP) in consecutive primary care patients for heart failure screening. DESIGN: Open, descriptive. SETTING: Three primary care clinics, university hospital. SUBJECTS: 291 consecutive patients, > or =40 years. MAIN OUTCOME MEASURES: p-BNP and general practitioners estimated probability of CHF. RESULTS: Median p-BNP was 29 ng/L. In 42% p-BNP was >40 ng/L in the first sample. In 41 patients further investigated, median p-BNP was 98 ng/L, with a correlation between p-BNP and physicians' estimation of probability of heart failure (r=0.469, p<0.0001). New York Heart Association class was correlated to p-BNP (r=0.343, p=0.034). No correlation between ejection fraction and p-BNP was seen. CONCLUSION:P-BNP concentrations in unselected primary care patients of 40 years of age or above were elevated in a larger proportion of patients than previously reported. Owing to the low specificity, p-BNP concentration limits have to be defined before the test can be used for screening in primary care.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Aged
- Atrial Natriuretic Factor/blood/*diagnostic use
- Biological Markers/*blood
- Family Practice/*methods
- Female
- Heart Failure
- Congestive/*diagnosis/epidemiology/prevention & control
- Hospitals
- University
- Humans
- Male
- Mass Screening/*methods
- Natriuretic Peptide
- Brain/blood/*diagnostic use
- Outpatient Clinics
- Hospital
- Predictive Value of Tests
- Prognosis
- Sensitivity and Specificity
- Sweden
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Schaufelberger, ...
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Bergh, Claes-Håk ...
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Caidahl, Kenneth ...
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Eggertsen, Rober ...
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Furenäs, Eva
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Lindstedt, Göran ...
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show more...
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Nilsson, Thomas
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Stefferud, Kari
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Swedberg, Karl, ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and General Practice
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Scandinavian jou ...
- By the university
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University of Gothenburg
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Karolinska Institutet