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Sökning: (WAKA:ref) lar1:(gu) srt2:(2000-2004) pers:(Swedberg Karl 1944) > Differences between...

Differences between patients with a preserved and a depressed left ventricular function: a report from the EuroHeart Failure Survey

Lenzen, M. J. (författare)
Scholte op Reimer, W. J. (författare)
Boersma, E. (författare)
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Vantrimpont, P. J. (författare)
Follath, F. (författare)
Swedberg, Karl, 1944 (författare)
Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
Cleland, J. (författare)
Komajda, M. (författare)
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 (creator_code:org_t)
Oxford University Press (OUP), 2004
2004
Engelska.
Ingår i: European heart journal. - : Oxford University Press (OUP). - 0195-668X. ; 25:14, s. 1214-20
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • AIMS: Due to a lack of clinical trials, scientific evidence regarding the management of patients with chronic heart failure and preserved left ventricular function (PLVF) is scarce. The EuroHeart Failure Survey provided information on the characteristics, treatment and outcomes of patients with PLVF as compared to patients with a left ventricular systolic dysfunction (LVSD). METHODS AND RESULTS: We performed a secondary analysis using data from the EuroHeart Failure Survey, only including patients with a measurement of LV function (n = 6806). We selected two groups: patients with LVSD (54%) and patients with a PLVF (46%). Patients with a PLVF were, on average, 4 years older and more often women (55% vs. 29%, respectively, p < 0.001) as compared to LVSD patients, and were more likely to have hypertension (59% vs. 50%, p < 0.001) and atrial fibrillation (25% vs. 23%, p = 0.01). PLVF patients received less cardiovascular medication compared to PLVF patients, with the exception of calcium antagonists. Multivariate analysis revealed that LVSD was an independent predictor for mortality, while no differences in treatment effect on mortality between the two groups was observed. A sensitivity analysis, using different thresholds to separate patients with and without LVSD revealed comparable findings. CONCLUSIONS: In the EuroHeart Failure Survey, a high percentage of heart failure patients had PLVF. Although major clinical differences were seen between the groups, morbidity and mortality was high in both groups.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

Aged
Female
Health Surveys
Heart Failure
Congestive/drug therapy/*mortality/physiopathology
Hospitalization
Humans
Male
Multivariate Analysis
Survival Analysis
Treatment Outcome
Ventricular Dysfunction
Left/drug therapy/*mortality/physiopathology
Ventricular Function
Left/physiology

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ref (ämneskategori)
art (ämneskategori)

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