Age, clinical presentation, and outcome of acute coronary syndromes in the Euroheart acute coronary syndrome survey

Rosengren, Annika,1951Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine (författare)

AIMS: Age is one of the most powerful determinants of prognosis in myocardial infarction, but there is comparatively little recent data across the whole spectrum of acute coronary syndromes (ACS). We examined the impact of increasing age on clinical presentation and hospital outcome in a large sample of patients with ACS. METHODS AND RESULTS: Patients (n = 10 253) from the Euroheart ACS survey in 103 hospitals in 25 countries were investigated. There was a significant inverse association between the age and the likelihood of presenting with ST-elevation. For each decade of life, the odds of presenting with ST-elevation decreased by 0.82 [95% confidence interval (CI) 0.79-0.84]; P < 0.0001. Elderly patients were considerably less often treated by cardiologists, less extensively investigated, and, when presenting with ST-elevation ACS, less likely to be treated with reperfusion. Compared with patients <55 years, the odds ratios of hospital mortality were 1.87 (1.21-2.88) at age 55-64, 3.70 (2.51-5.44) at age 65-74, 6.23 (4.25-9.14) at age 75-84, and 14.5 (9.47-22.1) among patients > or =85 years, with no major differences across different types of admission or discharge diagnoses. CONCLUSION: Elderly ACS patients were less likely to present with ST-elevation but had substantial in-hospital mortality, yet they were markedly less intensively treated and investigated.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
Adult
Age Distribution
Aged
Aged
80 and over
Coronary Angiography/statistics & numerical data
Coronary Disease/*mortality/radiography
Europe/epidemiology
Female
Hospital Mortality
Hospitalization/statistics & numerical data
Humans
Male
Middle Aged
Myocardial Infarction/*mortality/radiography
Prognosis
Risk Factors
Syndrome
Adult
MEDICINE

Wallentin, Lars,1943-Uppsala universitet,Institutionen för medicinska vetenskaper,UCR(Swepub:uu)larswall (författare)
Simoons, M. (författare)
Gitt, A. K. (författare)
Behar, S. (författare)
Battler, A. (författare)
Hasdai, D. (författare)
Göteborgs universitetInstitutionen för medicin, avdelningen för akut och kardiovaskulär medicin (creator_code:org_t)

Ingår i:Eur Heart J: Oxford University Press (OUP)27:7, s. 789-950195-668X1522-9645

Av författaren/redakt...: Rosengren, Annik ...; Wallentin, Lars, ...; Simoons, M.; Gitt, A. K.; Behar, S.; Battler, A.; visa fler...; Hasdai, D.; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

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