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Swedish obese subje...
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Sjöström, LarsGothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för kroppssammansättning och metabolism,Institute of Internal Medicine, Dept of Body Composition and Metabolism
(författare)
Swedish obese subjects (SOS). Recruitment for an intervention study and a selected description of the obese state
- Artikel/kapitelEngelska1992
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LIBRIS-ID:oai:gup.ub.gu.se/54481
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https://gup.ub.gu.se/publication/54481URI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Department of Medicine, Sahlgren's Hospital, University of Göteborg, Sweden. SOS (Swedish obese subjects) is an on-going intervention trial designed to determine whether the mortality and morbidity rates among obese individuals who lose weight by surgical means (gastric banding, vertical banded gastroplasty and gastric by-pass) differ from the rates associated with conventional treatment. For this purpose, the study is recruiting a sample of obese men and women who constitute a registry of potential subjects from which the participants are drawn. Eligibility criteria for participation in the registry were: age at application 37-57 years and BMI greater than or equal to 34 kg/m2 for men and greater than or equal to 38 kg/m2 for women. Before receiving a health examination, all patients complete extensive questionnaires on current and past health status, utilization of medical care and medications, socio-economic status, psychological profiles, dietary habits, physical activity, weight history, and familial disposition to obesity. Each surgical case is matched to its optimal control in the registry, to ensure that the two groups do not differ systematically with respect to any of 18 matching variables that may affect prognosis. The first 1006 subjects included in the registry have been studied with respect to morbidity and compared with on-going population studies of men and women in Göteborg, Sweden. The relative risks of prevalent disease and symptoms associated with obesity in 50-year-old males and females respectively were 4.3 and 4.7 (dyspnoea), 14.7 and 11.8 (angina), 6.3 (myocardial infarction, males only), 2.1 and 4.5 (hypertension), 5.2 and 6.6 (diabetes), 4.6 and 26.1 (claudication) and 1.7 and 1.8 (gall bladder disease). Correspondingly, obese males and females display elevations of systolic and diastolic blood pressure, fasting glucose, insulin, triglyceride, and uric acid levels. However, total cholesterol was not increased in obese males and was in fact significantly lower in obese compared with reference women. HDL-cholesterol was lower in obese than reference men (data were not available in reference women). The rate of taking sick pensions was over twice as high in SOS obese patients than in population controls. Finally, comparison of measurements with self-reported prevalence estimates revealed a considerable amount of previously undiagnosed hypertension and diabetes in the obese subjects. These data suggest that the excess health risks associated with obesity may not be fully appreciated. PMID: 1322873 [PubMed - indexed for MEDLINE]
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Larsson, B.
(författare)
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Backman, L.
(författare)
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Bengtsson, Calle,1934Gothenburg University,Göteborgs universitet,Institutionen för samhällsmedicin, Avdelningen för allmänmedicin,Institute of Community Medicine, Dept of Primary Health Care(Swepub:gu)xbengc
(författare)
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Bouchard, C
(författare)
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Dahlgren, S
(författare)
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Hallgren, P
(författare)
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Jonsson, E
(författare)
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Karlsson, J.
(författare)
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Lapidus, L
(författare)
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Lindroos, Anna-Karin,1958
(författare)
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Lindstedt, SvenGothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine(Swepub:gu)xlsvez
(författare)
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Lissner, Lauren,1956Gothenburg University,Göteborgs universitet,Institutionen för samhällsmedicin, Avdelningen för allmänmedicin,Institute of Community Medicine, Dept of Primary Health Care(Swepub:gu)xlisla
(författare)
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Narbro, Kristina,1953
(författare)
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Näslund, I
(författare)
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Olbe, L
(författare)
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Sullivan, Marianne,1943
(författare)
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Sylvan, A
(författare)
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Wedel, H
(författare)
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Ågren, G
(författare)
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Göteborgs universitetInstitutionen för invärtesmedicin, Avdelningen för kroppssammansättning och metabolism
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:International Journal of Obesity19, s. 465-479
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Sjöström, Lars
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Larsson, B.
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Backman, L.
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Bengtsson, Calle ...
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Bouchard, C
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Dahlgren, S
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Hallgren, P
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Jonsson, E
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Karlsson, J.
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Lapidus, L
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Lindroos, Anna-K ...
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Lindstedt, Sven
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Lissner, Lauren, ...
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Narbro, Kristina ...
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Näslund, I
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Olbe, L
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Sullivan, Marian ...
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Sylvan, A
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Wedel, H
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Ågren, G
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