The release of vitamin C from chewing gum and its effects on supragingival calculus formation.

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Lingström, Peter,1960Gothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för cariologi,Institute of Odontology, Department of Cariology (author)

The release of vitamin C from chewing gum and its effects on supragingival calculus formation.

Article/chapterEnglish2005

Publisher, publication year, extent ...

Wiley,2005

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LIBRIS-ID:oai:gup.ub.gu.se/55047
https://gup.ub.gu.se/publication/55047URI
https://doi.org/10.1111/j.1600-0722.2004.00177.xDOI

Supplementary language notes

Language:English

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

The aims of this study were to evaluate (i): whether vitamin C in chewing gum, alone or in combination with carbamide, influences calculus formation, and (ii) whether carbamide affects the release, stability and uptake of vitamin C in a chewing gum. In two test series (Series I and II), 30 subjects, all calculus formers, participated. They were instructed to chew on five (Series I) or 10 (Series II) pieces of gum per day for a period of 3 months. The chewing gums were: vitamin C (60 mg, Series I), non-vitamin C (Series I) and vitamin C + carbamide (30 mg + 30 mg, Series II). In both series, no gum was used as a negative control. Calculus formation was scored on three lingual sites on the six anterior mandibular teeth according to the Volpe-Manhold index. The effect on plaque and gingivitis was also determined. A significant reduction in the total calculus score was observed after the use of vitamin C (33%) and vitamin C + carbamide (12%) gums compared with no gum use; this reduction was most pronounced in the heavy calculus formers. A reduced amount of visible plaque was also observed after use of vitamin C and non-vitamin C gum, but only the vitamin C gum reduced the number of bleeding sites (37%). In a separate study, the release, stability and uptake of vitamin C were evaluated using the iodine titration method in both saliva and urine after exposure to the following gums: vitamin C + carbamide (30 mg + 30 mg) and vitamin C (30 mg). There was no indication that carbamide affected the release, stability or uptake of vitamin C when used in a chewing gum.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Odontologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Dentistry hsv//eng
Adult
Ascorbic Acid
administration & dosage
chemistry
Chewing Gum
Cross-Over Studies
Cuspid
pathology
Dental Calculus
metabolism
pathology
prevention & control
Dental Plaque
prevention & control
Diffusion
Double-Blind Method
Drug Combinations
Drug Stability
Female
Gingivitis
prevention & control
Humans
Incisor
pathology
Iodine
analysis
urine
Male
Mandible
Middle Aged
Saliva
chemistry
drug effects
metabolism
Urea
administration & dosage
chemistry

Added entries (persons, corporate bodies, meetings, titles ...)

Fure, Solveig,1941Gothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för cariologi,Institute of Odontology, Department of Cariology(Swepub:gu)xfurso (author)
Dinitzen, Bettina (author)
Fritzne, ChristinaGothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för oral mikrobiologi,Institute of Odontology, Department of Oral Microbiology(Swepub:gu)xfrich (author)
Klefbom, Carin,0Gothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för oral mikrobiologi,Institute of Odontology, Department of Oral Microbiology (author)
Birkhed, Dowen,1946Gothenburg University,Göteborgs universitet,Odontologiska institutionen, Avdelningen för cariologi,Institute of Odontology, Department of Cariology(Swepub:gu)xbirdo (author)
Göteborgs universitetOdontologiska institutionen, Avdelningen för cariologi (creator_code:org_t)

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In:European journal of oral sciences: Wiley113:1, s. 20-70909-88361600-0722

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