(hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) hsv:(Odontologi)) pers:(Hakeberg Magnus)
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- Coli, Pierluigi,1964Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology (author)
The effect of a dentifrice in the prevention of recurrent aphthous stomatitis.
- Article/chapterEnglish2004
Publisher, publication year, extent ...
- 2004
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/55475
- https://gup.ub.gu.se/publication/55475URI
- https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-4442URI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- PURPOSE: A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the efficacy of an experimental dentifrice on the prevention of recurrent aphthous stomatitis (RAS). MATERIAL AND METHODS: A 3-month pretrial period was used to self-record data pertaining to the frequency, ulcer size, duration, and pain associated with ulcers. Thirty-six participants, who reported at least 3 RAS episodes or 30 days with RAS during the pretrial period, completed the study. Following a stratified randomization for age, sex and disease severity, the participants received the experimental dentifrice (T) or the placebo (C). The test period comprised 3 months of self-evaluation of number of ulcers, size and location. Pain related to RAS was estimated by the use of a Visual Analogue Scale (VAS). RESULTS: Symptoms were found to decrease in both groups when the pretrial and test periods were compared, although no statistical difference was reached in the C group. A statistically significant difference between the two time periods was obtained for the T group concerning the number of days with ulcers (p < 0.025) and VAS (p < 0.010). Of more clinical importance was the observation that 50% of the patients in the T group reported a more than 50% reduction in days with ulcers compared to 17% in the C group. CONCLUSIONS: The dentifrice may be used as a treatment strategy for a subgroup of patients with RAS in view of the low adverse effects and the benefit of using a treatment modality that is a part of daily routines.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Odontologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Dentistry hsv//eng
- Adolescent
- Adult
- Aged
- Child
- Dentifrices
- analysis
- therapeutic use
- Double-Blind Method
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Pain Measurement
- Placebos
- Stomatitis
- Aphthous
- pathology
- physiopathology
- prevention & control
- Time Factors
- Adolescent
Added entries (persons, corporate bodies, meetings, titles ...)
- Jontell, Mats,1951Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology(Swepub:gu)xjonma (author)
- Hakeberg, Magnus,1954Jönköping University,Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology,HHJ, Avdelningen för naturvetenskap och biomedicin,HHJ. Centrum för oral hälsa(Swepub:hj)hakm (author)
- Göteborgs universitetOdontologiska institutionen (creator_code:org_t)
Related titles
- In:Oral health & preventive dentistry2:2, s. 133-411602-1622
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