Search: L773:1478 3231 >
The AST/ALT ratio a...
-
Nyblom, Helena,1968Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine
(author)
The AST/ALT ratio as an indicator of cirrhosis in patients with PBC.
- Article/chapterEnglish2006
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:gup.ub.gu.se/57766
-
https://gup.ub.gu.se/publication/57766URI
-
https://doi.org/10.1111/j.1478-3231.2006.01304.xDOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-34984URI
Supplementary language notes
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
OBJECTIVES: A non-invasive, simple and non-expensive test to predict cirrhosis would be highly desirable. The aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio has been proven to be such an indicator of cirrhosis in alcoholic liver disease, hepatitis C. AIM: To test whether the AST/ALT ratio is a marker of cirrhosis also in patients with primary biliary cirrhosis (PBC). METHODS: The study consisted of 160 patients. In 126 patients, we had clinical and laboratory data at the time of diagnosis and follow-up with outcome: liver-related death, liver transplantation and survival. In 121 patients, we had laboratory data and liver histology. RESULTS: We found that the AST/ALT ratio was significantly higher in cirrhotic patients than in non-cirrhotic patients. A high AST/ALT ratio was significantly associated with esophageal varices and ascites. In a multivariate analysis, bilirubin and ALP were predictors of poor prognosis. CONCLUSION: The AST/ALT ratio seems to be of clinical value as a hint to the diagnosis of cirrhosis in patients with PBC but not as a prognostic factor.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Björnsson, Einar,1958Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine(Swepub:gu)xbjoei
(author)
-
Simrén, Magnus,1966Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine(Swepub:gu)xsimrm
(author)
-
Aldenborg, Frank,1945Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för patologi,Institute of Biomedicine, Department of Pathology(Swepub:gu)xaldfr
(author)
-
Almer, Sven,1953-Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Gastroenterologi och hepatologi,Endokrin- och magtarmmedicinska kliniken US(Swepub:liu)sveal38
(author)
-
Olsson, Rolf,1936Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine(Swepub:gu)xolrol
(author)
-
Göteborgs universitetInstitutionen för medicin, avdelningen för invärtesmedicin
(creator_code:org_t)
Related titles
-
In:Liver international : official journal of the International Association for the Study of the Liver: Wiley26:7, s. 840-51478-32231478-3231
-
In:Liver International: Wiley26:7, s. 840-51478-3231
Internet link
Find in a library
To the university's database
- By the author/editor
-
Nyblom, Helena, ...
-
Björnsson, Einar ...
-
Simrén, Magnus, ...
-
Aldenborg, Frank ...
-
Almer, Sven, 195 ...
-
Olsson, Rolf, 19 ...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Gastroenterology ...
- Articles in the publication
-
Liver internatio ...
-
Liver Internatio ...
- By the university
-
University of Gothenburg
-
Linköping University