Preanalytical conditions that affect coagulation testing, including hormonal status and therapy

• Preanalytical conditions, be they due to the individual's physiologic state or to exogenous factors, can affect coagulation factors, in either a transient or a persistent manner, and need to be considered in laboratory testing. These conditions include physical and mental stress, diurnal variation, hormone levels and posture at the time of blood drawing. While testing of these factors has not been exhaustive and some results are conflicting, guidelines for testing conditions can be given.

Nyckelord

Anticoagulants/administration & dosage/therapeutic use

*Blood Coagulation

Blood Specimen Collection/*methods

Contraceptives

Oral/therapeutic use

Exercise

Female

Hormones/*blood

Humans

Indicators and Reagents

*International Normalized Ratio

Male

Menstrual Cycle

Pregnancy

*Prothrombin Time/instrumentation

Stress

Psychological

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