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  • Komajda, M. (author)

Management of octogenarians hospitalized for heart failure in Euro Heart Failure Survey I

  • Article/chapterEnglish2007

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  • Oxford University Press (OUP),2007

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  • LIBRIS-ID:oai:gup.ub.gu.se/66798
  • https://gup.ub.gu.se/publication/66798URI
  • https://doi.org/10.1093/eurheartj/ehl443DOI

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  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

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  • AIMS: Here, the aim is to study the management of octogenarians hospitalized for heart failure in Euro Heart Failure Survey I. Heart Failure (HF) is common in older people and associated with poor outcome. METHODS AND RESULTS: We compared clinical characteristics, treatment, and short-term outcomes in 2780 octogenarians (group A, median age 85 years) and in 7912 younger patients (group B, median age 69 years) enrolled in the Euro Heart Failure Survey I. There were 37% males in group A vs. 59% in group B (P < 0.001). Co-morbidities were more common in group A. Ejection fraction was measured only in 38% in group A vs. 65% in group B (P < 0.001) and when measured was preserved in 50 vs. 40% (P < 0.001). In-hospital and 12 weeks follow-up mortality were, respectively, 13 vs. 5% (P < 0.001) and 12 vs. 6% (P < 0.001) in groups A and B. Acute cardiac conditions and co-morbidity predicted mortality, whereas the use of angiotensin-converting enzyme inhibitor (ACE-I) and beta-blockers was associated with a better outcome. ACE-I and beta-blockers were used in 50 vs. 66% (P < 0.001) and 24 vs. 42% (P < 0.001) in groups A and B, respectively, whereas diuretics, digitalis, and nitrates were more commonly used in octogenarians. CONCLUSION: Preserved systolic function, multiple co-morbidities, and high mortality are observed in octogenarians with HF. In these patients, cardiac function is assessed in only a minority and treatments known to improve prognosis in younger patients under-utilized. Overall, the management of octogenarians with HF does not follow international guidelines.

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  • Hanon, O. (author)
  • Hochadel, M. (author)
  • Follath, F. (author)
  • Swedberg, Karl,1944Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine(Swepub:gu)xsweka (author)
  • Gitt, A. (author)
  • Cleland, J. G. (author)
  • Göteborgs universitetInstitutionen för medicin, avdelningen för akut och kardiovaskulär medicin (creator_code:org_t)

Related titles

  • In:Eur Heart J: Oxford University Press (OUP)28:11, s. 1310-80195-668X
  • In:European Heart Journal: Oxford University Press (OUP)28:11, s. 1310-81522-9645

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By the author/editor
Komajda, M.
Hanon, O.
Hochadel, M.
Follath, F.
Swedberg, Karl, ...
Gitt, A.
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Cleland, J. G.
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About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Cardiac and Card ...
Articles in the publication
Eur Heart J
European Heart J ...
By the university
University of Gothenburg

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Komajda, M.
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