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Evaluation of recon...
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Norberg, Pernilla,1970-Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet
(författare)
Evaluation of reconstruction techniques for lung single photon emission tomography: a Monte Carlo study.
- Artikel/kapitelEngelska2007
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United States :Lippincott Williams & Wilkins,2007
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LIBRIS-ID:oai:gup.ub.gu.se/67015
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https://gup.ub.gu.se/publication/67015URI
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https://doi.org/10.1097/MNM.0b013e3282f1acacDOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-21152URI
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BACKGROUND: In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM: To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtered back-projection (FBP) for lung SPECT with Tc. METHODS: The evaluation of the number of iterations used in OSEM was based on the image quality parameter contrast. The comparison between OSEM and FBP was based on trade-off plots between statistical noise and spatial resolution for different filter parameters, collimators and count-levels. A Monte Carlo technique was used to simulate SPECT studies of a digital thorax phantom containing two sets of activity: one with a homogeneous activity distribution within the lungs and the other with superposed high- and low-activity objects. Statistical noise in the reconstructed images was calculated as the coefficient of variation (CV) and spatial resolution as full width at half-maximum (FWHM). RESULTS: For the configuration studied, the OSEM reconstruction in combination with post-filtering should be used in lung SPECT studies with at least 60 MLEM equivalent iterations. Compared to FBP the spatial resolution was improved by about 1 mm. For a constant level of CV, a four-fold increase in count level resulted in an increased resolution of about 2 mm. Spatial resolution and cut-off frequency depends on what value of noise in the image is acceptable also increased by using a low-energy, high-resolution collimator for CV values above 3%. The choice of noise-reducing filter and cut-off frequency depends on what value of noise in the image is acceptable.
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Bake, Björn,1939Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine,Sahlgrenska universitetssjukhuset, Göteborg(Swepub:gu)xbakbj
(författare)
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Jacobsson, Lars,1947Göteborgs universitet, Göteborg(Swepub:gu)xjacla
(författare)
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Alm Carlsson, Gudrun,1939-Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Hälsouniversitetet,Radiofysikavdelningen(Swepub:liu)gudal03
(författare)
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Gustafsson, AgnethaÖstergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet(Swepub:liu)agngu51
(författare)
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Linköpings universitetMedicinsk radiofysik
(creator_code:org_t)
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Ingår i:Nuclear medicine communicationsUnited States : Lippincott Williams & Wilkins28:12, s. 929-360143-36361473-5628
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