The influence of Bio-Oss collagen on healing of an extraction socket: An experimental study in the dog.

• Background: Different approaches were advocated to preserve or improve the dimension and contour of the ridge following tooth extraction. In some of studies socket grafting apparently had a successful outcome while in other reports the benefits of such therapy were more questionable. Aim: The objective of the present experiment was to evaluate the effect on hard tissue modeling and remodeling of the placement of a xenograft in the fresh extraction socket in dogs. Material and Methods: Five mongrel dogs were used. Two mandibular premolars (4P4) were hemi-sected. The distal roots were carefully removed. In one socket, a graft consisting of Bio-Oss® Collage was placed while the contra-lateral site was left without grafting. After 3 months of healing, the dogs were euthanized and biopsies sampled. From each experimental site, 4 ground sections – 2 from the mesial root and 2 from the healed socket – were prepared, stained and examined in the microscope. Results: The placement of Bio-Oss® Collagen in the fresh extraction socket failed to inhibit the processes of modeling and remodeling that took place in the socket walls following tooth extraction. The biomaterial, however, apparently promoted de novo hard tissue formation, in particular in the cortical region of the extraction site. Hereby, the dimension of the hard tissue was maintained and the profile of the ridge was better preserved. Conclusion: The placement of a biomaterial in an extraction socket may promote bone modeling and at least temporarily compensate for marginal ridge contraction.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

biomaterial

dogs

histology

ridge augmentation

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