DISABKIDS Smiley questionnaire. The TAKE 6 Assisted Health-related Quality of Life measure for 4 to 7 year olds.

• The DISABKIDS Smiley TAKE 6 was developed to meet the need for a research instrument to measure the health-related quality of life (HrQoL) of children 4–7 years old. TAKE 6 is a European generic assisted-report questionnaire with a proxy version. The items of TAKE 6, scored using a five-point Likert scale, cover a single HrQoL domain. Child and parent focus groups identified the statements which, following a European pilot study, were reduced to six items. A field study of 435 children with a chronic disease in seven European countries revealed that the questionnaire had good reliability (inter-class correlation 0.69), had convergent validity with the KINDL-R (child quality of life questionnaire-revised) (rho 0.60) and satisfactory construct validity showing separation between severity and different medical conditions. The questionnaire was understandable by young children and could be completed within two minutes.

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