Hormones and drinking behaviour: new findings on ghrelin, insulin, leptin and volume-regulating hormones. An ESBRA Symposium report.

• There is growing evidence for a role of appetite-related peptides and volume-regulating hormones in alcoholism. In particular, recent evidence has suggested that hormones, such as ghrelin, insulin and leptin and volume-regulating hormones, could play a role in alcohol-seeking behaviour. The goal of this review is to discuss the results of recent preclinical and clinical investigations on this topic. The findings indicate that neuroendocrinological mechanisms are potentially involved in the neurobiology of alcohol craving. Accordingly, research on this topic could lead to possible development of new therapeutic approaches in the treatment of patients with alcohol problems.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Physiology (hsv//eng)

Keyword

Alcohol Drinking

physiopathology

psychology

Alcoholism

physiopathology

psychology

rehabilitation

Animals

Appetite Regulation

physiology

Atrial Natriuretic Factor

physiology

Ghrelin

physiology

Humans

Insulin

physiology

Leptin

physiology

Motivation

Peptide Hormones

physiology

Societies

Medical

Vasopressins

physiology

Publication and Content Type

ref (subject category)

art (subject category)