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Phenotypic and geno...
Phenotypic and genotypic characteristics of women in relation to personality traits.
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- Baghaei, Fariba, 1964 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Rosmond, Roland, 1966 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Landén, Mikael, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för klinisk neurovetenskap, Sektionen för psykiatri,Institute of Clinical Neurosciences, Section of Psychiatry
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- Westberg, Lars, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology
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- Hellstrand, Monika, 1955 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology
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- Holm, Göran, 1942 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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- Eriksson, Elias, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi,Institute of Physiology and Pharmacology, Dept of Pharmacology
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- Björntorp, Per, 1931 (author)
- Gothenburg University,Göteborgs universitet,Hjärt-kärlinstitutionen,Cardiovascular Institute
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(creator_code:org_t)
- 2003
- 2003
- English.
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In: International journal of behavioral medicine. - 1070-5503. ; 10:4, s. 365-78
- Related links:
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https://gup.ub.gu.se...
Abstract
Subject headings
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- The associations were examined in women between personality traits and steroid hormones, particularly androgens, as well as polymorphisms in genes regulating androgen concentration and effects. Women, all 42 years of age and premenopausal (n = 270), were recruited randomly. Conventional "masculine" and "feminine" personality traits were examined by questionnaire and set in relation to psychosocial and socioeconomic conditions, behavior in childhood, hormones, risk factors for disease, and polymorphisms in microsatellites in the CYP aromatase and the androgen receptor gene. The proportions of personality traits considered as being dominated by "masculinity" (M) or "femininity" (F) were 44.9%, respectively 15.0%, the rest consisting of a combination of M and F (33.2%) or "undifferentiated" (6.9%). M characteristics were positively associated with education, sporting, self-confidence, and good adaptation to work situation. M scores correlated with reports of "tomboyism" as girls. There was essentially no difference in hormones or disease risk factors between M and F women. The number of (CAG) repeats in the microsatellite of the transactivating domain of the androgen receptor was 19 (2.3; M and SD). M characteristics were more pronounced in the presence of longer repeat stretches (n > 20). No associations were found with F scores. There were no significant associations to the number of tetranucleotide repeats (TTTA) in the fourth introne of the aromatase gene. It was concluded that a majority of women showed M type of personality traits, associated with normal hormones, somatic health, and a long microsatellite in the transactivating domain of the AR gene.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- Adult
- Androgens
- genetics
- Aromatase
- genetics
- Female
- Gender Identity
- Genotype
- Humans
- Personality
- genetics
- Phenotype
- Polymorphism
- Genetic
- Psychosexual Development
- Questionnaires
- Receptors
- Androgen
- genetics
- Self Concept
- Socioeconomic Factors
- Sweden
Publication and Content Type
- ref (subject category)
- art (subject category)
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Baghaei, Fariba, ...
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Rosmond, Roland, ...
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Landén, Mikael, ...
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Westberg, Lars, ...
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Hellstrand, Moni ...
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Holm, Göran, 194 ...
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Eriksson, Elias, ...
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Björntorp, Per, ...
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- MEDICAL AND HEALTH SCIENCES
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and Basic Medicine
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University of Gothenburg